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MIC1

Victor ID 5160
Gene Name MIC1
Sequence Strain (Species/Organism) Toxoplasma gondii ME49
NCBI Gene ID 7896467
NCBI Protein GI 237838467
Locus Tag TGME49_091890
Genbank Accession DS984735
Protein Accession XP_002368531
Taxonomy ID 508771
Gene Starting Position 2137299
Gene Ending Position 2140428
Gene Strand (Orientation) -
Protein pI 4.94
Protein Weight 45255.12
Protein Length 456
DNA Sequence 
>gi|212659397:2137299-2140428 Toxoplasma gondii ME49 scf_1112359875384, whole genome shotgun sequence
TGTGGCGCTTTGTGGTTGAAGCGAGACAACTCGTTTTGAATGTTGTAGAGCCGACTGACCGTATAATACA
CTTGTATTTTGCAGCGTCACCAAACGAGTGGGATGATCTCTCGTCACTTGCTGCGTTCGCGCCCGTACGT
GAGATGCGTGGACGTATGACAATACGTATAAAACTGACAGGATTACACCATAATACATTTTGATTCACTA
CTCAAGAAACATCTGACCGCGTAACAAGAATTCGGGCAACATGCTGCATTAAAGAGATAAGCAAGAACCT
CAGAAAGTAGATTCAATACAAGGCCCCGAAATACGGTGGGACGGCATGCAACAGAAACACTGAGGGCGGA
ATCTCGAGAAAGCCACAGTTCCCCGTATGAAGTTATATCCGTATGTCATAGTCATTACACCTGCAAGAAC
TCCAACTCTACAAGAACCAGGACGCATATAGGTGTAATAGTGACGCATCTTCCACTGTTCAGGAACGATC
TGTATCTCACAAACTTCATCCTGATTTTGCCGAGATTGTCCCGTTCCTCCACAAGCATGCTCCAAAGAGT
ACTATAAATCAAGCAGAGACGGCCGTAGGACTCTCGCCAAGCGTCGTCACCACGAGCGTCGCTCCACTAC
CCACTCCTTGGAAACTAACCTCTTCACTTGAGCTGCATCCAGAATCTTCGACCACGTAAGCAGCTGATCC
TAAAGCAGCATTGAGCCTGGTGTAGTCGAGGACAACAGCGAGACGGCCTTTGTGTCCCAGACCTATCGTA
AGCACTGCGGGTCCTGCTGGCTCTTCCACTTCTACCACATCGAACGCCGAATTTGAGCCCGTCTGAAACT
TCAAAAATCCATCAAGGAAATTCGCGACGAGTGAATGACACGAGCCTACAGCAACATCCAGTTTAGTGGA
GATAAACGTGAGCGTTAGTTGCTGCCCCTCTTCGAGCGTCGCTTTCGTGCTGTCACCATGGATCTCGGTT
TTCGGCGTCTTCTCGGGAGATGTTGATTTCTCAGGCAGGTCTATGTTACCACCCTTCGTTGGATGGTCCG
GCTGAGCTTCTCCTCCAGGCGACTGTTCCTTACCGCCACCTCTCTCGTCCGAACGATCGGCGGGCTGTTG
CATCTCAGGCGGTTGTGACGGTGGCCCACCACCAGTTCGTGAAATCTGGCCACTTTCATCTAAACACACC
GGGGGATTCTCATCCTTCGGTAGGCAGACTTCAACTTCAGAACATGGGCTGTCGACGGATCCGATTGCCT
GGCGAATTCCTTCCTCTTCTGTATAATGCCGCTTGTCTAGTTCTGTCGACGTCCCTGCAGGTAACGGGGT
GCCGGCAAGAAAACGGGGAACGGATGAGCCATCGGTGGAAACTGGTAAAAGATGACTTCGATGGAAAAAC
ATGACCAGAACCACCCCGTTCTCCCCACAGACCGCACTACTCTTGTCCTGGCTTGATCATCAAGAAAAAA
ATTGACAACATCTGTGGTGTCGAGCATGACAGCGGTAAGGACGCAAAATGAGAGGTTGCAGCCGCAACTT
GTGGCGCTGTTTTTGCTTTCCCTGCATTTCCAACTTACCTCGTCGTCCTCCAGGGCAGTACCACGTTGTT
CCGCAGTTGCTCGCACACTCAGCATAAACCGAGTACAGCAAGCTGGCCTAAACAGTATTGACGACAGCAA
ACAATGCCAACCTAACATTCCTTCCATGTTCCTCCAGTCTCTGCAAAGAAAAGCTTAGAATGGATGTGTA
CACTGTTATCTGTTGTACCGCTGTGAAAAAATAATTAAAGAAAACATACACGCCACTAGATTTCTGCAGC
TCGTTTCGAGCGTCTGCCCATTAACTGGAAAAAACGGGAATGAACTGCGGTAAATAACCCCTCTTCACCT
TTCGTGGTGTTGCTTTGCCTCGCAGTTATGGACGGCATATCAGGCTTCCCTTTTCCACAAGATACAAAGT
TTTCTGTCCCCAACAAGATGCATACGCTGAGAAGGCGATGGTCTGAATACTGATGTACGGGTGCACTCTA
ACAGGTTCTTCCTCACCTTCTCGTAACACCTCCACGCAACCTCGACATTGTTTCCGAAGCCCTTCGACCT
CCTCGCAATGGTCCCTGGAAATTTGTCGTTACAGTACTTGTTGGCAGATGCTTGATAAGGACTGCAGAAC
CGTTGTACTCCTTCTTCGACCAATTTGGACAGTATCTCATGGCGCGTTGCGTGATTACTGTTTTGCCGGT
GTACGCCGCCAGGACACGGTATCGTGTGGCCACAGTCGTCCACGCAATTAACACCGTTGTTTTCTTGATT
GCTCTCCAGCAAAGAGGCTGTATCAAAGCATCTCCATTCAAGTGTATTTTGATGAGTAATGCCCACGGCG
TTTCGAGCTACTATCCGGCTAGAGGGCACACACATTTTACGAAGTCCGCCTTGGCAGAGTTCTGCAGCAA
TCTCTTGGCAGCGTTGGTCAAGCATCTGTTGTATATAACGTCCCGATGCCGGCGAATGAGAATGCGACGC
TGAAAAAACACCGACAGAATCGAGAGAGCCAGTTCACGTGTCGTCGCTGCAATTTCACCGCACGTGAAAC
GTCCAGTTTCAGCCACAGTAAACTCAGATAGAAGCCTTGAAAAAAGAGGACGACTGAGTGCGCTCGTACC
ATTCAAAGCGAGCCAATGGCTTGCGTTCCCTTGTCCAGCTGACTACTACTACGGGCAAATCTTGTACATC
ACGACAGCTGTGTGCATTGATCCAAAAAATCGTGCACCCATCAGTCCTTGGTCTACACCCCCGATATCCA
AGAACAAGAGCGATGTTAGCGAACGAACTGGAAACGTACCTTCTCCATATGCTTCTGGCCCAACGCCAAA
TAACACCGGCAATAGAACGGTGAGAAACAACGCCTGGCCCATCTTTGCAAATCCGTTCTAGGTCAACTAC
AGAATCGAGGCACGTGTACACAGCTGCATCAACAGATCAGCAGCCATGTGAGACGAAACCAACACACAAA
AACGCACTCCTGCAAGCTAGCTGACAGGAAAATAACTAAATTTTCTACAGCTTTCAGCCGGTGCGACGTC
TAGCAACACGAGAACCGCGTCGCACCAATAAGGAACGTAACATCGAAGTG
Protein Sequence 
>gi|237838467|ref|XP_002368531.1| microneme protein MIC1 [Toxoplasma gondii ME49]
MGQALFLTVLLPVLFGVGPEAYGEASHSHSPASGRYIQQMLDQRCQEIAAELCQGGLRKMCVPSSRIVAR
NAVGITHQNTLEWRCFDTASLLESNQENNGVNCVDDCGHTIPCPGGVHRQNSNHATRHEILSKLVEEGVQ
RFCSPYQASANKYCNDKFPGTIARRSKGFGNNVEVAWRCYEKASLLYSVYAECASNCGTTWYCPGGRRGT
STELDKRHYTEEEGIRQAIGSVDSPCSEVEVCLPKDENPPVCLDESGQISRTGGGPPSQPPEMQQPADRS
DERGGGKEQSPGGEAQPDHPTKGGNIDLPEKSTSPEKTPKTEIHGDSTKATLEEGQQLTLTFISTKLDVA
VGSCHSLVANFLDGFLKFQTGSNSAFDVVEVEEPAGPAVLTIGLGHKGRLAVVLDYTRLNAALGSAAYVV
EDSGCSSSEEVSFQGVGSGATLVVTTLGESPTAVSA
Molecule Role Virulence factor
Molecule Role Annotation Individual disruption of MIC1 or MIC3 genes slightly reduced virulence in the mouse, whereas doubly depleted parasites were severely impaired in virulence and conferred protection against subsequent challenge. (Cérède et al., 2005)
References