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SAG3

Victor ID 5159
Gene Name SAG3
NCBI Protein GI 323650767
Other Database IDs CDD:240383
CDD:252367
Taxonomy ID 5811
Gene Strand (Orientation) ?
Protein Name surface antigen 3
Protein Length 385
Protein Note Surface antigen (SAG) superfamily; Provisional
Protein Sequence
>gi|323650767|gb|ADX97439.1| surface antigen 3 [Toxoplasma gondii]
MQLWRRRAAGPASLGKQSLPLGCFFAAFGLCVLSAILGTGEHGLFVAAGKSRSKITYFGTLTQKAPNWYR
CSSTRAKEEVVGHVTLNKEHPDMTIECVDDGLGGEFLPLEGATSSYPRVCHIDAKDKGDCERNKGFLTDY
IPGAKQYWYKIEKVENNGEQSVLYKFTVPWIFLPPAKQRYKVGCRYPNHEYCFVEATVEPTPPMVEGKRV
TCGYPESGPVNLEVDLSKDANFIEIRCGEQHHPQPSTYTLQYCSGDSVDPQKCSPQSLTNIFYDYSSSWW
KGKLNGPDGATLTIPPGGFPEEDKSFLVGCSLTVDGPPFCNVKVRVAGNPRKWGRGGGGHPGSGGSQPET
DGETQAGTESSAGASSRMASVALAFLLGLLVHVAA

Molecule Role Virulence factor
Molecule Role Annotation the null SAG3 mutants show attenuated infectivity, with a markedly reduced capacity to cause mortality in mice, whereas both wild-type and complemented mutants that re-expressed SAG3 were lethal at the same doses. (Dzierszinski et al., 2000)
References