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LPG2

Victor ID 5155
Gene Name LPG2
Sequence Strain (Species/Organism) Leishmania major strain Friedlin
NCBI Gene ID 5655087
NCBI Protein GI 157876111
Locus Tag LMJF_34_3120
Genbank Accession FR796430
Protein Accession XP_001686416
Taxonomy ID 347515
Chromosome No 34
Gene Starting Position 1391742
Gene Ending Position 1392767
Gene Strand (Orientation) ?
Protein pI 9.68
Protein Weight 34288.83
Protein Length 341
DNA Sequence 
>gi|389595460:1391742-1392767 Leishmania major strain Friedlin complete genome, chromosome 34
CATGAACCACACTCGCGCTGTCATGGAGGCGATCCTCGCCGTCATCACGTATAGCTTCTGCAGCGTGAGC
ATGATTCTCGTGAACAAGCTAATCATGAACACGTACGACATGAACTTCCCATTCGGAATCCTGGTGCTGC
AGACTGGTGGTGCACTAGTGATTGTGGCGCTGGCGAAGGCAGCACGCTTCGTTGAGTACCCGGCCTTTTC
ATTCGACGTGGCGAAAAAGTGGCTTCCTCTTACTCTGCTCTTCGTGGCAATGCTATTCACATCCATGAAG
AGCTTGGCCACGATGTCCGTCGCGGCTCAGACGATTCTCAAGAATCTGGCCGTTATCTTGATTGCACTCG
GCGACAAATTCCTCTACGGCAAGGCGCAAACCCCGATGGTCTACTTTTCGTTTGCGTTGATGATCCTCGG
CAGCTTTCTTGGCGCCAAGGGCGATAAGTGGGTAACAGCGTGGGGTCTCATCTGGACGCTTCTTAACATT
GTCTCCACCGTCTCGTACACGCTGTACATGAAGGCTGTACTGGGCTCTGTCAGTAACTCGATCGGCCGTT
ACGGTCCTGTCTTCTACAACAACCTGCTGTCCCTACCCTTTTTCCTAATAATGGGTGTCGGGGAGATCAT
GCCGTTCTCGGCCGCAATCGGTGAGACAACCACGCTCGGTAAGCTGGTGCTGACGTTCTCGGTGCTGGTG
AGCTCCGTGATGACGTTCTCTGTCTTTTGGTGCATGTCTATAACCTCGCCCACCACAATGAGCGTCGTGG
GCTCACTGAACAAGATACCCCTCACTTTCCTGGGCATGCTGGCGTTCCACCAGTTCCCCACCGCAACGGG
TTATCTGGGTATCATGGTCGCGCTATCCGCAGGATTCCTATACACGCACCTCAACATCAGGGCGAACCGC
GCCAAGGCTTCTTCCGATTTGGAGCACCAGATGCAGCAGACCGGCAAGACGACAACGGAGTCGATCGTAC
TGGTGCGCACGGACGAGAACAGCAGTGACAACTTCAAATCTGAGTA
Protein Sequence 
>gi|157876111|ref|XP_001686416.1| lipophosphoglycan biosynthetic protein (lpg2) [Leishmania major strain Friedlin]
MNHTRAVMEAILAVITYSFCSVSMILVNKLIMNTYDMNFPFGILVLQTGGALVIVALAKAARFVEYPAFS
FDVAKKWLPLTLLFVAMLFTSMKSLATMSVAAQTILKNLAVILIALGDKFLYGKAQTPMVYFSFALMILG
SFLGAKGDKWVTAWGLIWTLLNIVSTVSYTLYMKAVLGSVSNSIGRYGPVFYNNLLSLPFFLIMGVGEIM
PFSAAIGETTTLGKLVLTFSVLVSSVMTFSVFWCMSITSPTTMSVVGSLNKIPLTFLGMLAFHQFPTATG
YLGIMVALSAGFLYTHLNIRANRAKASSDLEHQMQQTGKTTTESIVLVRTDENSSDNFKSE
Molecule Role Virulence factor
Molecule Role Annotation the lpg2(-)REV revertant was unable to synthesize LPG2-dependent PGs in the promastigote stage and thus remained highly attenuated in the ability to induce infection. (Späth et al., 2004)
References