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PDI

Victor ID 5154
Gene Name PDI
NCBI Protein GI 25990151
Other Database IDs CDD:233282
CDD:239259
CDD:239279
CDD:239280
CDD:239293
Taxonomy ID 5664
Gene Strand (Orientation) ?
Protein Name disulfide isomerase PDI
Protein Length 477
Protein Note protein disulfide isomerase, eukaryotic; TIGR01130
Protein Sequence 
>gi|25990151|gb|AAN75008.1| disulfide isomerase PDI [Leishmania major]
MQRSFLVFVLCALLFCVASAEVQVATKDNFDKVVIGDLTLVKFYAPWCGHCKTLAPEFVKAADMLAGIAT
LAEVDCTKEESLAEKYEIKGFPTLYIFRNGEKVKIYDGPRTAAGIASYMKAHVGPSMKAISTAEELEELK
KETFPVCVVKTASTDSEMASMITKVADSLRSQMNFVLVTDAAISPNDAMESVTVYRKNAEREAYTGATPM
TAESVKSFLTSAVLDYFGELGQESFQKYMEANKDKPLGWVFIDKNTDSALKGSLVAVAEKYRSQVLLTYI
DGDQYRPVSRQLGIPEDAKFPAFVVDFERRHHVMGTDTPVTSESVAAFVEKYVKGETKQTVMSDAIPAKE
TVNGLTTVVGQTFAKYTDGTQNVMLLFYAPWCGHCKKLHPVYDKVAKSFESENVIIAKMDATTNDFDREK
FEVSGFPTIYFIPAGKPPIVYEGGRTADEIQVFVKSHLTASAAPSGGPSGNSEEEDL
Molecule Role Virulence factor
Molecule Role Annotation Specific PDI inhibitors abolished the enzymatic activity of the recombinant protein and profoundly affected parasite growth. (Ben et al., 2002)
References