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hsp70

Victor ID 5151
Gene Name hsp70
NCBI Protein GI 12248795
Other Database IDs CDD:240227
CDD:212675
CDD:261574
Taxonomy ID 5811
Gene Strand (Orientation) ?
Protein Length 674
Protein Note heat shock 70 kDa protein; Provisional
Protein Sequence 
>gi|12248795|dbj|BAB20284.1| hsp70 [Toxoplasma gondii]
MGSSHHHHHHSSGLVPRGSHMLEMADSPAVGIDLGTTYSCVGVWKNDAVEIIANDQGNRTTPSYVAFTDT
ERLVGDAAKNQVARNPENTIFDAKRLIGRKFDDPSVQSDMKHWPFKVIAGPGDKPLIEVTYQGEKKTFHP
EEVSAMVLGKMKEIAEAYLGKEVKEAVITVLAYFNDSQRQATKDAGTIAGLSVLRIINEPTAAAIAYGLD
KKGCGEMNVLIFDMGGGTFDVSLLTIEDGIFEVKATAGDTHLGGEDFDNRLVDFCVQDFKRKNRGKDIST
NSRALRRLRTQCERTKRTLSSSIQATIEIDSLFEGIDYSVSISRARFEELCMDYFRNSLLPVEKVLKDSG
IDKRSVSEVVLVGGSTRIPKIQQLITDFFNGKEPCRSINPDEAVAYGAAVQAAILKGVTSSQVQDLLLLD
VALLSLGLETAGGVMTKLIERNTTIPTKKSQTFTTYADNQPGVLIQVYEGERAMTKDNNLLGKFHLDGIP
PAPRGVPQIEVTFDIDANGIMNVTAQDKSTGKSNQITITNDKGRLSASEIDRMVQEAEKYKAEDEQNKHR
VEAKNGLENYCYHMRQTLDDEKLKDKISSEDRDTANKAIQEALDWLDKNQLAEKEEFEAKQKEVESVCTP
IITKLYQAGAAAGGMPGGMGGMPGGMGGMPGGMGGMPGGMGSGC
Molecule Role Virulence factor
Molecule Role Annotation Virulent parasites with reduced HSP70 expression displayed reduced proliferation in vivo, as measured by the number of tachyzoites present in spleens of infected mice.
(Dobbin et al., 2002)
References