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aroB

Victor ID 514
Gene Name aroB
Sequence Strain (Species/Organism) Listeria monocytogenes EGD-e
NCBI Gene ID 985753
NCBI Protein GI 16803966
Locus Tag lmo1927
Genbank Accession AL591981
Protein Accession NP_465451
Other Database IDs UniProtKB-ID: AROB_LISMO
UniRef100: UniRef100_Q8Y5X6
UniRef90: UniRef90_Q71Y88
UniRef50: UniRef50_Q71Y88
UniParc: UPI00000551B0
EMBL: AL591981
EMBL-CDS: CAD00005.1
RefSeq_NT: NC_003210.1
GenomeReviews: AL591824_GR
KEGG: lmo:lmo1927
GenoList: LMO1927
HOGENOM: HBG632303
OMA: YINEFAL
ProtClustDB: PRK00002
BioCyc: LMON169963:LMO1927-MONOMER
Taxonomy ID 169963
Gene Starting Position 2002044
Gene Ending Position 2003141
Gene Strand (Orientation) -
Protein Name 3-dehydroquinate synthase
Protein pI 5.44
Protein Weight 38547.53
Protein Length 365
Protein Note catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
DNA Sequence 
>gi|16802048:2002044-2003141 Listeria monocytogenes EGD-e, complete genome
CTCAAATGACATTCCCTCCCTTTCGCATCACACGTTTATATGTTTCAAAAATCAAATCATCATCTGCTTT
AAAAATAACTGGTTTACCAATTTCTTCGAGTAAAACCATACTTATTTCATTAAAAGTTGTTTTTTTATCA
TGACGCATATTTTCCAGTATCTTGCTAAATGGAACTGAAGCGTCAAAAGTGGTATCATAGCCCAACTGTT
CTAGCCAAGTTTTAAATTCTGCTAAATCGAAATCCAGTCCGTAAATAGTCTCACTCATCGTGAGCGCATA
AATCATCCCATAAGTAATCGCCTCGCCGTGTAGCCATTTACCAAAGTTTCCATAAGCTTCTAGCGCATGA
CCAAATGTGTGACCAAAATTCAAATACGCACGGACGCCTTGCTCGGTTTCATCTTGCGCAACGATATTTG
CCTTAATTTCAATTCCGCGTTGTAAAAATGGCGTCAAATCCTTCGTATAAAAGTCTTTCGGCTCCGTAAA
GGTATCCATTAAAGCACGTAATAAAGTCAGGTCACTAATGAGCGCATGTTTAATCATTTCCGCAAAACCA
GAGCGCAATTCCCGTTCTGGCAAAGTAGCAAAAAACTGCGTATCATAAATGACTGCTTCTGGCTGGTAAA
AGTTACCAATCATATTTTTGCCAAGTGGATGATTGATCGCAACCTTGCCACCAACCGCACTATCATGCGC
AAGAACCGTCGTAGGTACTTGATAAAACGGAATTCCTCTCATGTACGTAGCGGCCACAAAACCACCTAAA
TCACCAATAACGCCTCCACCAAAAGCAATTAAAACCGCTTTACGATCAAGACCTGTTTCAATCATTTTTG
TCATCACGTCTTCATACACACGGAACGTTTTCGCTTCTTCGCCGTTTGGTGCCACATAATAAGTGACGAC
AGGTAAATCAGCGAGAACCGCATCAAGTTTCGCTTTATGAAGTTCCGCCACGTGTCCGTCTGTTAAGACA
AACACGTGAGAAAATTTAGCAAGGCTCTTTGTCCATTTTTCGCGGATGTCTTCTAATGCGAATTCATTAA
TATATACTGGATATGTTTTACTTTTAGCACGGACTGTAATTTCTGGCA
Protein Sequence 
>gi|16803966|ref|NP_465451.1| 3-dehydroquinate synthase [Listeria monocytogenes EGD-e]
MPEITVRAKSKTYPVYINEFALEDIREKWTKSLAKFSHVFVLTDGHVAELHKAKLDAVLADLPVVTYYVA
PNGEEAKTFRVYEDVMTKMIETGLDRKAVLIAFGGGVIGDLGGFVAATYMRGIPFYQVPTTVLAHDSAVG
GKVAINHPLGKNMIGNFYQPEAVIYDTQFFATLPERELRSGFAEMIKHALISDLTLLRALMDTFTEPKDF
YTKDLTPFLQRGIEIKANIVAQDETEQGVRAYLNFGHTFGHALEAYGNFGKWLHGEAITYGMIYALTMSE
TIYGLDFDLAEFKTWLEQLGYDTTFDASVPFSKILENMRHDKKTTFNEISMVLLEEIGKPVIFKADDDLI
FETYKRVMRKGGNVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Loeffler et al., 2006).
COG COG0337E, under E: Amino acid transport and metabolism
References
Loeffler et al., 2006: Loeffler DI, Schoen CU, Goebel W, Pilgrim S. Comparison of different live vaccine strategies in vivo for delivery of protein antigen or antigen-encoding DNA and mRNA by virulence-attenuated Listeria monocytogenes. Infection and immunity. 2006; 74(7); 3946-3957. [PubMed: 16790768].