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MNN21

Victor ID 5139
Gene Name MNN21
Sequence Strain (Species/Organism) Candida albicans SC5314
NCBI Gene ID 3648131
NCBI Protein GI 68491898
Locus Tag CaO19.8625
Genbank Accession AACQ01000293
Protein Accession XP_710268
Taxonomy ID 237561
Chromosome No R
Gene Starting Position 4983
Gene Ending Position 6965
Gene Strand (Orientation) -
Protein pI 7.12
Protein Weight 74140.12
Protein Length 660
Protein Annotation one of six mannosyltransferases
DNA Sequence 
>gi|68491903:4983-6965 Candida albicans SC5314 chromosome R Ctg19-20083, whole genome shotgun sequence
TTTAATCAGTTATATTCTGTGTACTTTCCAAAAATCTTAAATGCTCCAAAATCTCATCACATAAATCTGA
TTTTTTAACATCCTGAAAAATTTGTAGGTTAACATCATAAATACATAGTAAATATTTCATTCCTTCCCAT
TGAAACCATTCAAAATCATACCCAATTCTTTTTATCATACCTGGTCCATATAATCTAACTCTATTGCCTT
TAGCATCAAATATTTTCTTCTCTTGTTTTAACTTCCATGGATTCAATTTAGGGAAATTAGCATGGACAAA
TAAAATCTCTGGCCCCTTTTCCAAAACTTGATGTTGTAATTTGAATTTATGTTGTTTTTCTTTATCCTTT
TCTGGTATTTTGGCATATTGTTCTCGTAACTTGATATATTCCAAATCCTGTTGAGGATCAAATTGTCCCA
TTCCACATCCTTCGAAATCACCACCAGGCACTTTGAAATGGCCTAAAGACACCAAAAATTTGGCAACTTG
GTAATACCTTTTGCCTAACGTGACTGTAGCAGCCAAAAATGTCTCTTTGTCACCTTCACCATCTGATCCT
TGTGAAAATAATGGATAATAATGTGATGGCCCATATAAATTGTAATATAAAGCTAATAATAATGGCTTCA
AATGAGTCTTTTTCGAAATCAATAATTGACCTGATTCACTAGTAGGATCAGGTATGCTTCCTAACCGTTG
ATGTAATGGTATTTTATCTAATTCAACTGATCCTTTCTCAACTGATAAATCAGTGTATTGTCCTTCCACT
TCATTGTACTTACTACCCAAATATTTTTCGCTGACATCAATGTCAGCAATGTTGTAGTAATATGGAGATG
TGGCACGTTTCCAATAGTCTGGCCAGACCACCAACCCATAAGATTTAAATGGGTCATTTTCAAATAGCTC
TTCTGGTGAATGTGCAGGGATATTATCACTATCAAGCAACAACACATTCTCAAAACTGGATAATAATATC
GCCAATGCTTTATATTGATAACCTTTGAATTCAAACTTGTTAGCAAAGCTATCCAGATTATCTTTGTTGG
GGTTCATTAATTGATTTTTCATATATATACAACGGGCGTCTAATTCCGGTAATATTCTATTACACAAATC
AGATTCATACTCTTCTATTTTAGGAATGAATACTTCAATAGGCAAATGACATCCAACTGCACGTAATGAC
TTTATTGATAATAATGTAAGCCAATTGAAACTTCCACCAGCAACGTAAACTATCCCATTCTTCTTGTATA
ATCCATCGGGGGCATCTTCCGGTAAATTCTCAACAACGTATTTGTGAGATTTTTTCATGGCGGCCAATTC
TTCGTTACTCAATTGTAAAAACTGGGATAAATATTTCTCACTGAATATAGTATCGTCATCGGCTAATGAA
TCAAATCGAGCATGATATATTCTTTTCTTAGAAGGATAAGTGTTTAATTGTGACACACTGGGTTTGGCTT
GATAAAATATTTTAAAAATATTGTCGAAAAATTCGTATCCTTGTTGTAGTCTTTTTTGTTCAAACGGGTG
TAATCTATTGTATTTTTCTTGTTGTTCATTGATTAGCTTTAAATTCAATTGATAGGCCTCATCCGACACT
AACGATTTCAGCAGTGTTTTCGTTGTAGGCTCTTTTGCATGCTGCTGTTGTTGTTGTTGCTGTTTGTGTT
GTGAAATTTCAGATGCACCTGATTCAACGCCGACTTCTTGATTGTTGTTTGGATTAACTTGAGGTTTCTT
TTCTTCAAAAGGTTTGGTTTTCGGTGGAAACAACGCCATAGTTATCGATTCCCATAATGAACGATGATAT
GTACCTTTTTCATTGATAATTGCTGAATTATCTTCAGCGGGAAGATTACTCCAATATGAATATATAAGAA
ATATTATAATGACCAGTAAGAATATGGAATTAATGAAGATATACTTGTGACGACGACGAAACAATCGTAG
CCTATAAGTAAGTTGTTGAAACA
Protein Sequence 
>gi|68491898|ref|XP_710268.1| hypothetical protein CaO19.8625 [Candida albicans SC5314]
MFQQLTYRLRLFRRRHKYIFINSIFLSVIIIFLIYSYWSNLPAEDNSAIINEKGTYHRSLWESITMALFP
PKTKPFEEKKPQVNPNNNQEVGVESGASEISQHKQQQQQQQHAKEPTTKTSSKSLVSDEAYQLNLKLINE
QQEKYNRLHPFEQKRLQQGYEFFDNIFKIFYQAKPSVSQLNTYPSKKRIYHARFDSLADDDTIFSEKYLS
QFLQLSNEELAAMKKSHKYVVENLPEDAPDGLYKKNGIVYVAGGSFNWLTLLSIKSLRAVGCHLPIEVFI
PKIEEYESDLCNRILPELDARCIYMKNQLMNPNKDNSDSFANKFEFKGYQYKALAILLSSFENVLLLDSD
NIPAHSPEELFENDPFKSYGLVVWPDYWKRATSPYYYNIADIDVSEKYLGSKYNEVEGQYTDLSVEKGSV
ELDKIPLHQRLGSIPDPTSESGQLLISKKTHLKPLLLALYYNLYGPSHYYPLFSQGSDGEGDKETFLAAT
VTLGKRYYQVAKFLVSLGHFKVPGGDFEGCGMGQFDPQQDLEYIKLREQYAKIPEKDKEKQHKFKLQHQV
LEKGPEILFVHANFPKLNPWKLKQEKKIFDAKGNRVRLYGPGMIKRIGYDFEWFQWEGMKYLLCIYDVNL
QIFQDVKKSDLCDEILEHLRFLESTQNITD
Molecule Role Virulence factor
Molecule Role Annotation In Candida albicans, the mannosyltransferase, Mnn2, gene family is comprised of six members (MNN2, MNN21, MNN22, MNN23, MNN24 and MNN26) .Deletion of all MNN2 gene family members increased the average survival of the moth larvae by 50%, and the sextuple mutant was attenuated in virulence with 100% of mice surviving infection with the sextuple mutant.(Hall et al., 2013)
References