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MDV076

Victor ID 5115
Gene Name MDV076
Sequence Strain (Species/Organism) Gallid herpesvirus 2
NCBI Gene ID 4811549
NCBI Protein GI 125745114
Locus Tag MD5V_076
Genbank Accession AF243438
Protein Accession YP_001033993
Taxonomy ID 10390
Gene Starting Position 134866
Gene Ending Position 137275
Gene Strand (Orientation) +
Protein Name oncoprotein MEQ
Protein pI 5.4
Protein Weight 36130.99
Protein Length 339
DNA Sequence 
>gi|125745044:134866-137275 Gallid herpesvirus 2, complete genome
GATGTCTCAGGAGCCAGAGCCGGGCGCTATGCCCTACAGTCCCGCTGACGATCCGTCCCCCCTCGATCTT
TCTCTCGGGTCGACTTCGAGACGGAAAAAAAGGAAAAGTCACGACATCCCCAACAGCCCCTCCAAACACC
CCTTCCCTGACGGCCTATCTGAGGAGGAGAAACAGAAGCTGGAAAGGAGGAGAAAAAGGAATCGTGACGC
CGCTCGGAGAAGACGCAGGAAGCAGACGGACTATGTAGACAAACTCCATGAAGCATGTGAAGAGCTGCAG
AGGGCCAATGAACACCTACGTAAGGAAATTCGAGATCTAAGGACTGAGTGCACGTCCCTGCGTGTACAGT
TGGCTTGTCATGAGCCAGTTTGCCCTATGGCGGTACCCCTAACGGTGACCCTTGGACTGCTTACCACCCC
GCACGATCCCGTTCCTGAACCTCCCATTTGCACTCCTCCACCTCCCTCACCGGATGAACCTAACGCTCCA
CATTGCTCCGGTTCCCAACCTCCTATCTGTACCCCCCCTCCTCCCGATACGGAGGAACTTTGCGCCCAGC
TCTGCTCGACCCCACCACCTCCCATCTCTACTCCCCATATTATCTACGCTCCGGGGCCTTCCCCCCTCCA
ACCTCCTATCTGTACCCCCGCTCCTCCCGATGCGGAGGAGCTTTGCGCCCAGCTCTGCTCGACCCCACCA
CCTCCCATCTGTACTCCCCATTCCCTCTTCTGCCCTCCCCAGCCTCCATCTCCGGAGGGCATCTTCCCTG
CATTGTGTCCTGTTACCGAGCCGTGTACCCCTCCATCGCCGGGGACGGTTTACGCTCAGCTTTGTCCTGT
TGGCCAGGTTCCCCTTTTTACCCCATCTCCCCCACATCCGGCTCCGGAGCCGGAGAGGCTTTATGCTCGT
CTTACCGAGGATCCCGAACAGGATTCCTTGTATTCGGGCCAGATTTATACTCAGTTTCCCTCGGATACTC
AGTCTACGGTCTGGTGGTTTCCAGGTGACGGGAGACCCTGATGATCCGCATTGTGACTCTCAGCAGCACA
TCGTCTATGCCCCATGTTTCTTCTCCCCTAGTTATATATAATAGTTTTCATAGTTTCGGGAAGATCAACA
TAAAGGAAAGGGTTAAAGGCATTATTTATCGATTTACTGACATAAAAAAATCCTCTGGGGTAACAAATTT
TCCTTACCGTGTAGCTTAGACTCGGAAGAACTATTTTGAGTTACATGGTCAGGGGATTTGTTGGCTCCAG
GAGTTCCGAAGTATGAGATAAACTTAGCTATGTGGAAAACTTCTGGGGCAACATCTCTCGGCCCCAGACT
GCTTAAATGGCAAATTCTCGTTCTATACAGAACGGTTGGGGAAGGGGAGGGGGGGTATATGGAGTATTAT
TCGGGATATGGCTTCTATGAAGCCTGCGGTAAGTTTTCCAGGCTCAAAAACTATGCCTGGCTGTTTTTTT
TTTAAGAAGGGATATGGACATCGCACATTAAGGAATATTAAAGATAACAGGATGGACATTCGGATGTAAA
AGGAATAAGCGAAACCTTTAGCAGATGTGAGTTAATGCAGTCTCGTATAATTCGGTGGTGCTGATTAGGT
TATCGTAAGGAACAACACGATTGATCTCTCATCCGCGTCCCAGCAATCAGGCCTATGTCCCTCTCCTGTG
GCCAGCTCACTGGCTGTGCACTGTGCGATTCTAAGTGCTACAGTCGTGAGCAGATCAATGGATCGGGGCT
CGCGCAACACTACTGTAATTAAATATTCGTTTATGAATTATGCAAATATGCACAGATAATATATACAGGG
ATGCACAGACATACTCCTATGCACCGATACACAGGCACATAGGCAGATGTCGACATTAACGAATATACAG
GCACGGACCTCCAGGAACATATGGAAAATACCTCATCGCAGAGACGCTTATGCAGGAGTAATCTGCGTTA
AGTCGTTACTGGATTGTAACGGCTATCCGGAGACTCTCTTCCCCTTTTGCTTGTTCACTGTGCGGCATTA
TTACATTTACACCGGTAATGCTGCGCATGAAAGAGCGAACGGAACGAGGCTCGTACGACATTACAAGAAT
AGTTTGAATTCTCGGGATAATCTCCCGATGGCCTCCCCCTTATGCTTTCTCTACGATGTGGCATTGTTTA
CGCGGCAGTGCCACGTGTGAGGGGACGATCGGGACGGGATCCATTACGTAAAATTTAGATCTTTTGTAGA
AATTCAATTCCCTTCCCCTTTTACTTTGTTTGATGTGTGCCACTGTTGTACCGATAGTGCCGCGCGTGAA
AGAGTGAACGGGAAGGGCTTACGTAAAGAACTGTCGGTGCCGGTACGGGGGGAAGCTGTAACGCATTTCG
AGTCTTGATAAAGCAGAGCATGAAAATTAA
Protein Sequence 
>gi|125745114|ref|YP_001033993.1| oncoprotein MEQ [Gallid herpesvirus 2]
MSQEPEPGAMPYSPADDPSPLDLSLGSTSRRKKRKSHDIPNSPSKHPFPDGLSEEEKQKLERRRKRNRDA
ARRRRRKQTDYVDKLHEACEELQRANEHLRKEIRDLRTECTSLRVQLACHEPVCPMAVPLTVTLGLLTTP
HDPVPEPPICTPPPPSPDEPNAPHCSGSQPPICTPPPPDTEELCAQLCSTPPPPISTPHIIYAPGPSPLQ
PPICTPAPPDAEELCAQLCSTPPPPICTPHSLFCPPQPPSPEGIFPALCPVTEPCTPPSPGTVYAQLCPV
GQVPLFTPSPPHPAPEPERLYARLTEDPEQDSLYSGQIYTQFPSDTQSTVWWFPGDGRP
Molecule Role Virulence factor
Molecule Role Annotation Deletion of Meq gene significantly decreased immunosuppression and oncogenic properties of very virulent MDV strains. (Li et al., 2011)
References
Li et al., 2011: Li Y, Sun A, Su S, Zhao P, Cui Z, Zhu H. Deletion of the Meq gene significantly decreases immunosuppression in chickens caused by pathogenic Mareks disease virus. Virology journal. 2011; 8; 2. [PubMed: 21205328].