Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

NS4B

Victor ID 5113
Gene Name NS4B
NCBI Protein GI 27885153
Taxonomy ID 11096
Gene Strand (Orientation) ?
Protein Name nonstructural protein NS4B
Protein Length 347
Protein Note Pestivirus type 2
Protein Sequence 
>gi|27885153|ref|NP_777504.1| nonstructural protein NS4B [Classical swine fever virus]
AQGDVQRCVEAMTNYAREGIQFMKSQALKVKETPTYKETMNTVTDYVKKFMEALADSKEDILRYGLWGTH
TALYKSISARLGSETAFATLVVKWLAFGGESIADHVKQAATDLVVYYIINRPQFPGDTETQQEGRKFVAS
LLVSALATYTYKSWNYNNLSKIVEPALATLPYAATALKLFAPTRLESVVILSTAIYKTYLSIRRGKSDGL
LGTGVSAAMEIMSQNPVSVGIAVMLGVGAVAAHNAIEASEQKRTLLMKVFVKNFLDQAATDELVKESPEK
IIMALFEAVQTVGNPLRLVYHLYGVFYKGWEAKELAQRTAGRNLFTLIMFEAVELLGVDSEGKIRQL
Molecule Role Virulence factor
Molecule Role Annotation NS4B.VGIv showed an attenuated phenotype in swine, displaying reduced replication in the oronasal cavity and limited spread from the inoculation site to secondary target organs (Fernandez-Sainz et al., 2009).
References
Fernandez-Sainz et al., 2009: Fernandez-Sainz I, Holinka LG, Gavrilov BK, Prarat MV, Gladue D, Lu Z, Jia W, Risatti GR, Borca MV. Alteration of the N-linked glycosylation condition in E1 glycoprotein of Classical Swine Fever Virus strain Brescia alters virulence in swine. Virology. 2009; 386(1); 210-216. [PubMed: 19203774].