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clpB

Victor ID 511
Gene Name clpB
Sequence Strain (Species/Organism) Listeria monocytogenes EGD-e
NCBI Gene ID 985416
NCBI Protein GI 16804245
Locus Tag lmo2206
Genbank Accession AL591982
Protein Accession NP_465730
Other Database IDs UniProtKB-ID: CLPB_LISMO
UniRef100: UniRef100_Q8Y570
UniRef90: UniRef90_Q71XF9
UniRef50: UniRef50_Q6GIB2
UniParc: UPI0000055487
EMBL: AL591982
EMBL-CDS: CAD00284.1
RefSeq_NT: NC_003210.1
GenomeReviews: AL591824_GR
KEGG: lmo:lmo2206
GenoList: LMO2206
HOGENOM: HBG413133
OMA: PLGREDV
ProtClustDB: CLSK564825
BioCyc: LMON169963:LMO2206-MONOMER
Taxonomy ID 169963
Gene Starting Position 2294554
Gene Ending Position 2297154
Gene Strand (Orientation) -
Protein Name hypothetical protein
Protein pI 4.7
Protein Weight 91113.85
Protein Length 866
DNA Sequence 
>gi|16802048:2294554-2297154 Listeria monocytogenes EGD-e, complete genome
GTTATTCTGTGACTTTAAAAGTAAATTCTTTATCTGCTAAATCAATTTCCACGGATGAATGTGGCATGAT
TTTACCAGAGACAATTTCTCTTGCAAGTGGTGTTTCGACATGACGCACAATATAGCGTTTAAGTGGTCGT
GCTCCGTATACCGGATCATAAGCTTCCTCCGCAATAAAGGCTTTTGCATCATCGGAAATAGTGATTGTAA
TTTCTTGGTCGGCTAAACGGATTTGAAGTTCTTCTACTAATTTCTCCACAATACCTTTAATATCAGCAAG
TGTTAGTGGTTTAAATAGAATAATATCATCTACGCGGTTTAAGAATTCTGGTTTAAATTCACTTTGTAAA
ATTTGCATTACATCTGATTCTAATTCCGGTGAAATTTCGCCTTCTTCGGTTCTTTCAAGTAATAAATTAG
AGCCAATATTTGACGTCATAATAATTACTGTATTTTTAAAATCAATTAATCGACCTTGTGAATCTGTGAT
ACGTCCATCGTCAAGTACTTGTAATAGTATGTTAAATACATCTGGATGAGCTTTTTCGATTTCATCAAGT
AGGACGATCGAATAAGGGTTTCGTCTTACAGCTTCAGTAAGTTGACCACCTTCCTCATAACCAATGTAAC
CTGGAGGAGCTCCGACAAGTCTTGATACGGAATGTTTCTCCATGTATTCAGACATATCAATTCGAATCAT
GTGATCTTCGGAATCAAACATATTAAATGCAAGTGCTTTAGCAAGTTCTGTTTTACCCACACCTGTTGGT
CCTAAGAAAATAAAGGAGCCTATTGGGCGTTTCGGATCTTTAATTCCTGCACGAGCTCGTAAGACAGCAT
CACTCACTAATTGGACGGCATCATCTTGACCAATTACTTTTTGATGAAGGACATCTGCTAATTTAAGCAG
TTTTTCGCGTTCTCCTTCTACTAATTTAGTCACCGGAATCCCTGTCCAACGTCCGACGATTTCTGCAATT
TCATTTTCTGTTACTTCTTCTTGTAAAATCCGATCTTCTTGTGCTGTTTTTTCGCGATTTTCTGCTTCTA
ACTCAAGCAATTCTTTTTCCACAGCCGGGATTCTACCGTGGCGTAATTCTGCTGCTTTGTTTAAATCATA
ATTATTTTCTGCTTCTTCTAATTCATGGCGTAAATGGTCGATTTGCTCCCGGACCTCACGAATTTTACTG
ATTTCGTTTTTCTCGGATTCCCATTTGGACTTCATTTGGTTGGCTTCTTCTTTGTAGTCAGCCAGCTCGC
GTTGCAATATTTCTAAACGGCGTTCACTCGCTGGATCTTTTTCTTCTTTTAGTGCTGCTTCCTCAATTTC
TAATTGCATTACTTTTCTAGTTACTTCATCGAGTTCACTTGGCATCGAGTCAATTTCGACACGAATAGTT
GCGCATGCTTCATCTACTAAGTCAATTGCTTTGTCCGGCAAGAAGCGGTCAGTAATATAACGATTAGAAA
GACTCGCAGCTGCAACTAAAGCATTGTCATGAATATTTACCCCGTGATGAATTTCAAAACGTTCTTTTAA
CCCGCGTAAAATGGAAACCGTATCTTCCACTGTTGGTTCTGGGACAAGCACTTTTTGGAAACGTCTTTCT
AGTGCAGCATCTTTTTCGATATATTGGCGATATTCATCCAATGTAGTTGCACCGATGCAGTGCAGTTCTC
CGCGGGCAAGCATCGGTTTTAACATATTTCCTGCGTCCATTGCGCCGTCTGTTTTACCTGCGCCGACAAT
CGTATGAATTTCATCAATAAAGAGTAAAATTTGACCATCACTTTGTTTTACTTCTTGGAGTACTGCTTTC
AATCGTTCTTCAAATTCACCGCGGTACTTAGCTCCAGCAATAAGGGAACCAATGTCGAGTGAGATAATCG
TTTTATCTTTCAGTCCTTCTGGCACGTCTTTTCGAACGATACGTTGCGCTAATCCTTCGACAATGGCTGT
TTTACCAACACCTGGTTCACCTATTAGAACTGGATTGTTTTTTGTTTTTCTAGATAAAATTCGGATAACG
TTACGAATTTCTGCATCGCGTCCGATTACTGGATCGAGTTTGCCGCTTCTAACTTCCGCGACTAAATCAC
GACCATATTTTGTTAAAGCTTCATAGTTTTCTTCTGCATTTTGAGAAGTCACTCTTTTCCCTCCTCTGAT
TTTTAAAATTGCTTCTTTAATTTGTTTTTTAGCTTTATGTTGATTTTTAAGCTCGGCTGTAATTGGATTC
GATTTTTGATCCATAACAGCTAAGATAAGATGTTCTGTTGAGACAAAATCATCTTCTAATTGTTGTTGTT
CTTTTTCTGCATCCCTCATTAGTTGGAAAAGAGCTTGGCTCATTGCTTGGCCATAATTCACGCCACTTCC
TGAAACTACTGGGATTTTTTCCAAAGTATTCTCTATTACTTTTTGAAGTGCATCTGTATCAACTTCCGCT
ACATCATAGACTCGCTTTGCAAAGTCGCTTTCTGTTAATAACACTTTAAAAACGTGTGCAACGTCAATTT
CTTGATGTTCTGATGCAATAGCTAGATTTTGTGCGTCCGCAATTGTTTGCTGGACTTGTTGTGTAAATTT
TTGTAAATCCA
Protein Sequence 
>gi|16804245|ref|NP_465730.1| hypothetical protein lmo2206 [Listeria monocytogenes EGD-e]
MDLQKFTQQVQQTIADAQNLAIASEHQEIDVAHVFKVLLTESDFAKRVYDVAEVDTDALQKVIENTLEKI
PVVSGSGVNYGQAMSQALFQLMRDAEKEQQQLEDDFVSTEHLILAVMDQKSNPITAELKNQHKAKKQIKE
AILKIRGGKRVTSQNAEENYEALTKYGRDLVAEVRSGKLDPVIGRDAEIRNVIRILSRKTKNNPVLIGEP
GVGKTAIVEGLAQRIVRKDVPEGLKDKTIISLDIGSLIAGAKYRGEFEERLKAVLQEVKQSDGQILLFID
EIHTIVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLDEYRQYIEKDAALERRFQKVLVPEPTVEDTVS
ILRGLKERFEIHHGVNIHDNALVAAASLSNRYITDRFLPDKAIDLVDEACATIRVEIDSMPSELDEVTRK
VMQLEIEEAALKEEKDPASERRLEILQRELADYKEEANQMKSKWESEKNEISKIREVREQIDHLRHELEE
AENNYDLNKAAELRHGRIPAVEKELLELEAENREKTAQEDRILQEEVTENEIAEIVGRWTGIPVTKLVEG
EREKLLKLADVLHQKVIGQDDAVQLVSDAVLRARAGIKDPKRPIGSFIFLGPTGVGKTELAKALAFNMFD
SEDHMIRIDMSEYMEKHSVSRLVGAPPGYIGYEEGGQLTEAVRRNPYSIVLLDEIEKAHPDVFNILLQVL
DDGRITDSQGRLIDFKNTVIIMTSNIGSNLLLERTEEGEISPELESDVMQILQSEFKPEFLNRVDDIILF
KPLTLADIKGIVEKLVEELQIRLADQEITITISDDAKAFIAEEAYDPVYGARPLKRYIVRHVETPLAREI
VSGKIMPHSSVEIDLADKEFTFKVTE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant displayed 100 fold decrease in virulence in bacteria, also attenuated in mice (Chastanet et al., 2004).
COG COG0542O, under O: Posttranslational modification, protein turnover, chaperones
References
Chastanet et al., 2004: Chastanet A, Derre I, Nair S, Msadek T. clpB, a novel member of the Listeria monocytogenes CtsR regulon, is involved in virulence but not in general stress tolerance. Journal of bacteriology. 2004; 186(4); 1165-1174. [PubMed: 14762012].