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aroA

Victor ID 510
Gene Name aroA
Sequence Strain (Species/Organism) Listeria monocytogenes EGD-e
NCBI Gene ID 985307
NCBI Protein GI 16803640
Locus Tag lmo1600
Genbank Accession AL591979
Protein Accession NP_465125
Other Database IDs UniProtKB-ID: Q8Y6T2_LISMO
UniRef100: UniRef100_C1KVP7
UniRef90: UniRef90_C1KVP7
UniRef50: UniRef50_P39912
UniParc: UPI00000554D5
EMBL: AL591979
EMBL-CDS: CAC99678.1
RefSeq_NT: NC_003210.1
PDB: 3NVT
GenomeReviews: AL591824_GR
KEGG: lmo:lmo1600
GenoList: LMO1600
HOGENOM: HBG575990
OMA: VPILKQE
ProtClustDB: PRK12595
BioCyc: LMON169963:LMO1600-MONOMER
Taxonomy ID 169963
Gene Starting Position 1644105
Gene Ending Position 1645190
Gene Strand (Orientation) -
Protein Name bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase
Protein pI 5.22
Protein Weight 37005.8
Protein Length 361
Protein Note catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
DNA Sequence 
>gi|16802048:1644105-1645190 Listeria monocytogenes EGD-e, complete genome
GTTACTTTATTTTATGTGGTACTAAGTTACTTGCTAAAATTGCATTCCAGAATTCTTCAAATTCAGGAAT
ATCCATTTGTTGTGCAGAATCCGATAATGCAACTGCAGGGTCTGGATGAACTTCAGCCATTACACCGTCT
GCTTCGATAGCTAGAGCAGCTTTCGCACATGGAAGTAATAAATCTTTTCGGCCAGTAGAATGCGTCACGT
CAACCATAACTGGTAAATGGGTTTCTTTTTTCAAAATTGGAACGGCAGAAATATCAAGTGTATTTCTTGT
CGCTTTTTCATATGTGCGGATACCACGTTCGCATAAGATGATTTTGCCATTTCCTTGTGACATGATATAT
TCAGCAGCACCAATGAATTCTTCAATCGTAGCAGATAAACCACGTTTTAGTAAGATTGGTTTGTCCACAC
GGCCAGCTGCTTTTAGTAATTCGAAGTTTTGCATGTTTCTTGCGCCAATTTGAATAACATCTACATAATC
AAGTGCAACTTCAATATCAGCCGGCGTAACGATTTCACTAATAACACCTAAACCGTATTCATCAGATACA
CGTTTTAAAATTTTCAGTCCTTCTAAACCTAATCCTTGGAAGTCATATGGGCTAGTACGAGGTTTAAATG
CGCCACCACGAATAAGTTTTAAGCCTTTCGCTTTAATGGATTCAGCAACCGCAGCAACTTGTTCATAAGA
TTCCACTGAACATGGACCGAAAACAAATACTGGTTCGCCATTCCCAATTGGCAAGCCTTTTACTGTAACT
ATCGTATCTTCTTTTTTATTTTTTCTAGAAACGAGTAATGCTTTAGAGTGATCTTCTTCTTGAAGCTCTA
ATCCCGCTTTAAAAATTTCTTTAAATAATTTTTGAACCGTACTATCTTCAAAAGGTCCTTCATTTGCTGC
AAGAATCGTGTTAAGCATTTCTCTTTCACGTAATGGATCAAAACGAAGAGAACCTTGAGTTCCTTTAATT
TTGCCAATTTCTTGTACCAAATTAGCACGTTTGCTAATTAATTCTAGCAAATCAATATTTAATTGATCCA
CCTGTGTTCTAAGTTCCTCTAAATTTGTATTAACCA
Protein Sequence 
>gi|16803640|ref|NP_465125.1| bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase [Listeria monocytogenes EGD-e]
MVNTNLEELRTQVDQLNIDLLELISKRANLVQEIGKIKGTQGSLRFDPLREREMLNTILAANEGPFEDST
VQKLFKEIFKAGLELQEEDHSKALLVSRKNKKEDTIVTVKGLPIGNGEPVFVFGPCSVESYEQVAAVAES
IKAKGLKLIRGGAFKPRTSPYDFQGLGLEGLKILKRVSDEYGLGVISEIVTPADIEVALDYVDVIQIGAR
NMQNFELLKAAGRVDKPILLKRGLSATIEEFIGAAEYIMSQGNGKIILCERGIRTYEKATRNTLDISAVP
ILKKETHLPVMVDVTHSTGRKDLLLPCAKAALAIEADGVMAEVHPDPAVALSDSAQQMDIPEFEEFWNAI
LASNLVPHKIK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Loeffler et al., 2006).
COG COG2876E, under E: Amino acid transport and metabolism
References
Loeffler et al., 2006: Loeffler DI, Schoen CU, Goebel W, Pilgrim S. Comparison of different live vaccine strategies in vivo for delivery of protein antigen or antigen-encoding DNA and mRNA by virulence-attenuated Listeria monocytogenes. Infection and immunity. 2006; 74(7); 3946-3957. [PubMed: 16790768].