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fgf

Victor ID 5095
Gene Name fgf
Sequence Strain (Species/Organism) Bombyx mori NPV
NCBI Gene ID 1488656
NCBI Protein GI 9630842
Locus Tag Bmnpvgp026
Genbank Accession L33180
Protein Accession NP_047439
Taxonomy ID 271108
Gene Starting Position 23406
Gene Ending Position 23954
Gene Strand (Orientation) +
Protein Name FGF
Protein pI 9.96
Protein Weight 19778.39
Protein Length 182
Protein Note 20771 Da primary translation product
DNA Sequence 
>gi|9630816:23406-23954 Bombyx mori NPV, complete genome
CATGTATCGTTTGCTGGCACTTGTAACTCTAGCCTCTATGGCTGACTGCTCAGCTCTGCTGACACACATC
ACGGGCACGTCTATTCCCGGCCGGCTGTTTATTAACCGGCGGTTTTTGGCAGTAAATCCAAACGGAACCG
TTTACGGCGGAACCATTGAATCGGACAACGCCGACACCACATTCAAGCGCCTTGCCGTTGACAGAAATCG
CATCGTCATTCAAAACGCCATTACGTGTGTGTACCTGTGCATAGACCGGTGTGGCCAACTGTACGGATCA
AAAACTTTATCCGATGATTGCTTTATGAGGGAAATTATGGAAAAAAATAACTACAATACGTATTATAAAA
TGTACGATCGCAAGTTGACGTATGTGGCACTGAAGAACGACGGTACTCCCCGAAAACTACAGATTTCAAA
GGGCCGCAAGCTGGGCAAGTTTAGCGTGTACGCCATGACTTTATTGAAACGCTTAAGTTTTCCTATATAC
ACGTCGTGTCCTAATATAAAAAATGAAACTATTGTTCAACATCGTAAATGTCATGTGTA
Protein Sequence 
>gi|9630842|ref|NP_047439.1| FGF [Bombyx mori nucleopolyhedrovirus]
MYRLLALVTLASMADCSALLTHITGTSIPGRLFINRRFLAVNPNGTVYGGTIESDNADTTFKRLAVDRNR
IVIQNAITCVYLCIDRCGQLYGSKTLSDDCFMREIMEKNNYNTYYKMYDRKLTYVALKNDGTPRKLQISK
GRKLGKFSVYAMTLLKRLSFPIYTSCPNIKNETIVQHRKCHV
Molecule Role Virulence factor
Molecule Role Annotation we generated a BmNPV mutant, BmIEGFP, possessing an ie-1 promoter-driven green fluorescent protein gene, and its derivative BmIEGFP/FGFD, in which vfgf was partially deleted from the genome of BmIEGFP. Intrahemocoelic and oral infection experiments using these viruses revealed that the loss of functional vFGF reduces viral infectivity in B. mori hemocytes.(Katsuma et al., 2008)
References
Katsuma et al., 2008: Katsuma S, Horie S, Shimada T. The fibroblast growth factor homolog of Bombyx mori nucleopolyhedrovirus enhances systemic virus propagation in B. mori larvae. Virus research. 2008; 137(1); 80-85. [PubMed: 18611420].