Victors

m136
Victor ID	5085
Gene Name	m136
NCBI Protein GI	157676230
Other Database IDs	UniProtKB/TrEMBL: A8E1Q1
Taxonomy ID	69156
Gene Strand (Orientation)	?
Protein Name	m136 protein
Protein Length	253
DNA Sequence
Protein Sequence	>gi\|157676230\|emb\|CAP08172.1\| m136 protein [Murine cytomegalovirus (strain K181)] MFLPTAAAWLFLAHGVASQITTTVSQTRGYTTARNKTYIEWCFRTNERFASLNVTWNRTLYDTEILFETS WTRFTTERCVARKLVGAEDAMIQILRFDPDDKNMEELRVKFEGTINHDSTGSFVSYINTQSGRWSVEKVM KVEISFVCELKVSEDAARYSCEPEGYGWLTKGYLTATVRVNGSEHSIHLPEPGGAYIEYERGSFLSGYLG PGGPLVTVTVLQPCPPREIDLIIELHPRYKLYQRFVIPERRGE
Molecule Role	Virulence factor
Molecule Role Annotation	No differences were observed in viral yield, plaque size, and plaque morphology between the parental strain and any of the m136 mutant viruses. In vivo analysis using a SCID mouse virulence model showed a consistently measurable attenuated phenotype for all three m136 mutants. The results showed that although the m136 gene was not essential for replication in vitro or in vivo, an intact m136 gene was necessary to yield wild type virulence during infection of the host. (Visalli et al., 2007)
References	*Visalli et al., 2007:* Visalli RJ, Nicolosi DM, Irven K, Khan T, Visalli MA. Characterization of the murine cytomegalovirus m136 gene. Virus genes. 2007; 34(2); 117-126. [PubMed: 17143724].


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