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NS1

Victor ID 5082
Gene Name NS1
Sequence Strain (Species/Organism) Bovine respiratory syncytial virus
NCBI Gene ID 1489807
NCBI Protein GI 9631268
Locus Tag BovRSVgp01
Genbank Accession AF092942
Protein Accession NP_048048
Taxonomy ID 11246
Gene Starting Position 45
Gene Ending Position 571
Gene Strand (Orientation) +
Protein Name mRNA
Protein pI 6.66
Protein Weight 14749.75
Protein Length 136
DNA Sequence 
>gi|9631267:45-571 Bovine respiratory syncytial virus, complete genome
CGGGGCAAATAAAACCTTGAAAGGGAGTTTTCCCCTCTCTTCTTTCTACAGAAAATGGGCAGTGAAACAT
TGAGTGTAATTCAAGTCAGATTAAGGAATATATATGATAATGATAAAGTAGCATTGCTTAAAATAACATG
TCATACCAATAGATTAATACTTCTAACTCACACATTGGCCAAATCAGTCATACATACAATTAAATTAAGT
GGTATAGTATTCATACATATTATAACCAGTAGTGATTACTGTCCTACATCTGATATTATCAATAGTGCCA
ATTTCACTTCAATGCCTATATTACAAAATGGAGGATATATATGGGAATTGATGGAGTTAACACATTGTTT
CCAAACAAACGGTTTAATAGATGATAATTGTGAAATAACATTTTCTAAAAGGTTAAGTGATTCAGAATTA
GCTAAATATTCAAATCAATTATCTACTCTTCTTGGTCTGAATTAGAGCCCTAAATCAATAGCCAACACCA
GATGGACTAAGCTAACTAAATGTAATAGTTTATAAAA
Protein Sequence 
>gi|9631268|ref|NP_048048.1| NS1 [Bovine respiratory syncytial virus]
MGSETLSVIQVRLRNIYDNDKVALLKITCHTNRLILLTHTLAKSVIHTIKLSGIVFIHIITSSDYCPTSD
IINSANFTSMPILQNGGYIWELMELTHCFQTNGLIDDNCEITFSKRLSDSELAKYSNQLSTLLGLN
Molecule Role Virulence factor
Molecule Role Annotation the NS deletion mutants replicated to wild-type rBRSV levels in cells lacking a functional IFN-alpha/beta system, their replication was severely attenuated in IFN-competent cells and in young calves. (Valarcher et al., 2003)
References
Valarcher et al., 2003: Valarcher JF, Furze J, Wyld S, Cook R, Conzelmann KK, Taylor G. Role of alpha/beta interferons in the attenuation and immunogenicity of recombinant bovine respiratory syncytial viruses lacking NS proteins. Journal of virology. 2003; 77(15); 8426-8439. [PubMed: 12857912].