Victors

P-C
Victor ID	5076
Gene Name	P-C
NCBI Nucleotide GI	332738
NCBI Protein GI	332739
Protein Accession	AAA46866.1
Other Database IDs	CDD:145131
Taxonomy ID	11216
Gene Strand (Orientation)	?
Protein Name	P mRNA
Protein Length	604
Protein Note	Paramyxovirinae P phosphoprotein C-terminal region; pfam01806
DNA Sequence	>gi\|332738\|gb\|M14890.1\|PIFP Human parainfluenza virus type 3, mRNA encoding phosphoprotein (P) and nonstructural protein C, complete cds AGGATTAAAGAATCCTATCATACCAGAACATAGAGTGGTAAATTTAGAGTCTGCTTGCAACTCAATCAAT AGAGAGTTGATGGAAAGCGATGCTAAAAACTATCAAATCATGGATTCTTGGGAAGAGGAACCAAGAGATA AATCAACTAATATCTCCTCGGCCCTCAACATCATTGAATTCATACTCAGCACCGACCCCCAAGAAGACCT ATCGGAAAACGACACAATCAACACAAGAACCCAGCAACTCAGCGCCACCATCTGTCAACCAGAAATCAAA CCAACAGAAACAAGTGAAAAAGTTAGTGGATCAACTGACAAAAATAGACAGTCTGGGTCATCACACGAAT GTACAACAGAAGCAAAAGATAGAAATATTGATCAGGAAACTGTACAGGGAGGATCTGGGAGAAGAAGCAG CTCAGATAGTAGAGCTGAGACTGTGGTCTCTGGAGGAATCTCTGGAAGCATCACAGATTCTAAAAATGGA ACCCAAAACACGGAGAATATTGATCTCAATGAAATTAGAAAGATGGATAAGGACTCTATTGAGAGGAAAA TGCGACAATCTGCAGATGTTCCAAGCGAGATATCAGGAAGTGATGTCATATTTACAACAGAACAAAGTAG AAACAGTGATCATGGAAGAAGCTTGGAACCTATCAGTACACCTGATACAAGATCAATGAGTGTTGTTACT GCTGCGACACCAGATGATGAAGAAGAAATACTAATGAAAAATAGTAGGATGAAGAAAAGTTCTTCAACAC ACCAAGAAGATGACAAAAGAATTAAAAAAGGGGGGGGGGGAAAAGGGAAAGACTGGTTTAAGAAATCAAG AGATACTGACAACCAGACATCAACATCAGATCACAAACCCACATCAAAAGGGCAAAAGAAAATCTCAAAA ACAACAACCACCAACACCGACACAAAGGGGCAAACAGAAACACAGACAGAATCATCAGAAACACAATCCC CATCATGGAATCCCATTATCGACAACAACACTGACCGAACCGAACAGACAAGCACAACCCCCCCAACAAC AACTCCCAGATCAACTCGTACAAAAGAATCAATCCGAACAAACTCTGAATCCAAACCCAAGACACAAAAG ACAATTGGAAAGGAAAGGAAGGATACAGAAGAGAGCAATCGATTTACAGAGAGGGCAATTACTCTATTGC AGAATCTTGGTGTAATTCAATCTACATCAAAACTAGATTTATATCAAGACAAACGAGTTGTATGTGTAGC AAATGTACTAAACAATGTAGATACTGCATCAAAGATAGACTTCCTAGCAGGATTAGTCATAGGGGTTTCA ATGGACAATGACACAAAATTAATACAGATACAAAATGAAATGTTAAACCTCAAAGCAGATCTAAAGAGAA TGGACGAATCACATAGAAGATTGATAGAAAATCAAAGAGAACAACTGTCATTGATCACATCGTTAATTTC AAATCTTAAAATTATGACTGAGAGAGGAGGAAAGAAAGACCAAAATGAATCCAATGAGAGAGTATCTATG ATCAAGACAAAATTGAAAGAAGAAAAGATCAAGAAAACCAGGTTTGACCCACTTATGGAGGCACAAGGTA TTGACAAGAATATACCTGATCTATATCGACATGCAGGAAATACGTTAGAGAACGACGTACAAGTTAAATC AGAGATATTAAGTTCATACAACGAGTCAAATGCAACAAGACTAATACCCAGAAAAGTGAGCAGTACAATG AGATCACTAGTTGCAGTCATCAACAACAGCAATCTCCCACAAAGCAGAAAACAATCATATATAAACGAAC TCAAACATTGCAAAAGTGATGAAGAAGTATCTGAATTGATGGACATGTTCAATGAAGATGTTAACAATTG CTAAAGATCAAATAAAAAAAACAACACCGAATAAATAGACAAGAAACAACAGTAGATCAAAACCTATCAA CACACACAAAATCAAGCAGAGTGAAACAATAGACATCAATCAATATACAAATAAG
Protein Sequence	>gi\|332739\|gb\|AAA46866.1\| phosphoprotein [Human parainfluenza virus 3] MESDAKNYQIMDSWEEEPRDKSTNISSALNIIEFILSTDPQEDLSENDTINTRTQQLSATICQPEIKPTE TSEKVSGSTDKNRQSGSSHECTTEAKDRNIDQETVQGGSGRRSSSDSRAETVVSGGISGSITDSKNGTQN TENIDLNEIRKMDKDSIERKMRQSADVPSEISGSDVIFTTEQSRNSDHGRSLEPISTPDTRSMSVVTAAT PDDEEEILMKNSRMKKSSSTHQEDDKRIKKGGGGKGKDWFKKSRDTDNQTSTSDHKPTSKGQKKISKTTT TNTDTKGQTETQTESSETQSPSWNPIIDNNTDRTEQTSTTPPTTTPRSTRTKESIRTNSESKPKTQKTIG KERKDTEESNRFTERAITLLQNLGVIQSTSKLDLYQDKRVVCVANVLNNVDTASKIDFLAGLVIGVSMDN DTKLIQIQNEMLNLKADLKRMDESHRRLIENQREQLSLITSLISNLKIMTERGGKKDQNESNERVSMIKT KLKEEKIKKTRFDPLMEAQGIDKNIPDLYRHAGNTLENDVQVKSEILSSYNESNATRLIPRKVSSTMRSL VAVINNSNLPQSRKQSYINELKHCKSDEEVSELMDMFNEDVNNC
Molecule Role	Virulence factor
Molecule Role Annotation	Results indicate that the C, D, and V proteins of HPIV3 each has a role in virus replication in vitro, in vivo, or both, and define mutations that might be useful for the development of a vaccine against HPIV3. (Durbin et al., 1999)
References	*Durbin et al., 1999:* Durbin AP, McAuliffe JM, Collins PL, Murphy BR. Mutations in the C, D, and V open reading frames of human parainfluenza virus type 3 attenuate replication in rodents and primates. Virology. 1999; 261(2); 319-330. [PubMed: 10497117].


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P-C