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UK

Victor ID 5066
Gene Name UK
NCBI Nucleotide GI 2905984
NCBI Protein GI 2905985
Protein Accession AAC03759.1
Taxonomy ID 10497
Gene Strand (Orientation) ?
Protein Name virulence determinant
DNA Sequence 
>gi|2905984|gb|AF015681.1| African swine fever virus isolate Zi virulence determinant (UK) gene, complete cds
ATGTCTACTCATGATAATTCTCCAAAAGAGAAACCAGTTGATATGAACAATATATCTGAGAAATTATCTG
TCGTGGATAATGCACCCGAGAAACCAGCTGGAGCGAATCATATACCTGAGAAGTCGGCCCGCGAAATGAC
ATCATCAGAATGGATTGCTGAATATTGGAAAGGTATAAAACGTGGAAATGACGTGCCATGTTGTTGTCCA
AGAAAAATGACCAGTGCAGACAAAAAGTTTTCAGTATTTGGTAAGGGATCCCTAATACGCTCCATCCAGA
AGAATAATTAAAA
Molecule Role Virulence factor
Molecule Role Annotation Although deletion of UK did not affect the growth characteristics of the virus in macrophage cell cultures, deltaUK exhibited reduced virulence in infected pigs.
(Zsak et al., 1998)
References
Zsak et al., 1998: Zsak L, Caler E, Lu Z, Kutish GF, Neilan JG, Rock DL. A nonessential African swine fever virus gene UK is a significant virulence determinant in domestic swine. Journal of virology. 1998; 72(2); 1028-1035. [PubMed: 9444996].