Victors

LAT
Victor ID	5060
Gene Name	LAT
NCBI Nucleotide GI	3002817
Taxonomy ID	10298
Gene Strand (Orientation)	?
Protein Note	latency-associated transcript gene
DNA Sequence	>gi\|3002817\|gb\|AF041142.1\| Human herpesvirus 1 latency-associated transcript (LAT) gene, partial sequence TGCAGCCGGGGCGGCCAAGGGGCGTCGGCGACATCCTCCCCCTAAGCGCCGGCCGGCCGCTGGTCTGTTT TTTGTTTTCCCCGTTTCGGGGGTGGGGGGGGGTTACGGTTTCTGTTTTTTAAACCCGTCTGGGGTGTTTT TCGTTCCGTCGCCGGGATGTTTCGTTCGTTCGGCCCCTCACGGGGCGAAGGCCGCGTACGGCCCGGGACG AGGGGCCCCCGACCGCGGCGGTCCGGGCCCCGTCCGGGCCCGCTCGCCGGCACGCGACGCGAAAAAGGCC CCCCGGAGGCTTTTCCGGGTTCCCGGCCCGGGGCCTGAGATAAACAATCGGGGTTACCGCCAACGGCCGG CCCCCGTGGCGGCCCGGCCCGGGGCCCCGGCGGACCCAAGGGGCCCCGGCCCGGGGCCCCACAACGGCCC GGCGCATGCGCTGTTTTTTTTTTTTCCTCGGTGTTCTGCCGGGCTCCGTCGCCTTTCCTGTTCTCGCTTC TTCCCCCCCCCCCCTTCTTCACCCCCAGTACCCTCCTCCCTCCCTTCCTCCCCCGTTATCCCACTCGTCG AGGGCGCCCCGGTGTCGTTCAACAAAGACGCCGCGTTTCCAGGTAGGTTAGACACCTGCTTCTCCCCAAT AGAGGGGGGGGACCCAAACGACAGGGGGCGCCCCAGAGGCTAAGGTCGGCCACGCCACTCGCGGGTGGGC TCGTGTTACAGCACACCAGCCCGTTCTTTTCCCCCCCTCCCACCCTTAGTCAGACTCTGTTACTTACCCG TCCGACCACCAACTGCCCCCTTATCTAAGGGCCGGCTGGAAGACCGCCAGGGGGTCGGCCGGTGTCGCTG TAACCCCCCACGCCAATGACCCACGTACTCCAAGAAGGCATGTGTCCCACCCCGCCTGTGTTTTTGTGCC TGGCTCTCTATGCTTGGGTCTTACTGCCTGGGGGGGGGGAGTGCGGGGGAGGGGGGGGTGTGGAAGGAAA TGCACGGCGCGTGTGTACCCCCCCCCCAAAGTTGTTCCTAAAGCGAGGATATGGAGGAGTGGCGGGTGCC GGGGGACGGGGGTGATCTCTGGCACGCGGGGGGGGGAAGGGTCGGGGGAGGGGGGGATGGGGTACCGGCC CACCTGGCCGACGCGGGTGCGCGTGCCTTTGCACACCAACCCCACGTCCCCCGGCGGTCTCTAAGAAGCA CCGCCCCCCCTCCTTCATACCACCGAGCATGCCTGGGTGTGGGTTGGTAACCAACACGCCCATCCCCTCG TCTCCTGTGATTCTCTGGCTGCACCGCATTCTTGTTTTCTAACTATGTTCCTGTTTCTGTCTCCCCCCCA CCCCTCCGCCCCACCCCCCAACACCCACGTCTGTGGTGTGGCCGACCCCCTTTTGGGCGCCCCGTCCCGC CCCGCCACCCCTCCCGTCCTTTGTTGCCCTATAGTGTAGTT
Molecule Role	Virulence factor
Molecule Role Annotation	These results suggest for the first time (i) that regions past the first 1.5 kb of LAT can compensate for deletions in the first 1.5kb of LAT and may therefore play a role in LAT dependent spontaneous reactivation and (ii) that regions of LAT affect viral virulence. (Perng et al., 1999)
References	*Perng et al., 1999:* Perng GC, Slanina SM, Yukht A, Drolet BS, Keleher W Jr, Ghiasi H, Nesburn AB, Wechsler SL. A herpes simplex virus type 1 latency-associated transcript mutant with increased virulence and reduced spontaneous reactivation. Journal of virology. 1999; 73(2); 920-929. [PubMed: 9882292].


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LAT