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RRVgp2 |
| Victor ID |
5022 |
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Gene Name |
RRVgp2 |
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NCBI Gene ID |
1489707
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Protein Name |
envelope glycoprotein E2 |
|
Molecule Role |
Virulence factor |
|
Molecule Role Annotation |
In day-old mice, RRV dE2,with a 21-nucleotide deletion in the gene coding for the envelope glycoprotein E2, induced less severe symptoms of hind leg paralysis than did RRV T48. In week-old mice, RRV dE2 induced no detectable symptoms even when injected at high doses. (Vrati et al., 1986) |
| References |
Vrati et al., 1986: Vrati S, Faragher SG, Weir RC, Dalgarno L. Ross River virus mutant with a deletion in the E2 gene: properties of the virion, virus-specific macromolecule synthesis, and attenuation of virulence for mice. Virology. 1986; 151(2); 222-232. [PubMed: 3010551].
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