Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

cheA

Victor ID 502
Gene Name cheA
Sequence Strain (Species/Organism) Listeria monocytogenes EGD-e
NCBI Gene ID 985032
NCBI Protein GI 16802734
Locus Tag lmo0692
Genbank Accession AL591976
Protein Accession NP_464219
Other Database IDs UniProtKB-ID: CHEA_LISMO
UniRef100: UniRef100_Q48768
UniRef90: UniRef90_Q48768
UniRef50: UniRef50_Q48768
UniParc: UPI00000556A2
EMBL: X76170
EMBL: AL591976
EMBL-CDS: CAA53765.1
EMBL-CDS: CAC98770.1
RefSeq_NT: NC_003210.1
GenomeReviews: AL591824_GR
KEGG: lmo:lmo0692
GenoList: LMO0692
HOGENOM: HBG705053
OMA: VYMVFEQ
ProtClustDB: CLSK564049
BioCyc: LMON169963:LMO0692-MONOMER
Taxonomy ID 169963
Gene Starting Position 726412
Gene Ending Position 728268
Gene Strand (Orientation) +
Protein Name two-component sensor histidine kinase CheA
Protein pI 4.58
Protein Weight 63369.21
Protein Length 618
DNA Sequence 
>gi|16802048:726412-728268 Listeria monocytogenes EGD-e, complete genome
CATGACTACAAATATGTTAGACCTGTTTATAGAAGAAGCTTCAGAACATTTACAGGCGCTAAATGATAAT
CTGTTACAGCTTGAGAAAGACCCGACGAACGGTCAGTTAGTAAGTGAAATTTTCCGTTCAGCACATACGT
TTAAAGGGATGTCCGCAACGATGGGCTTCCAGCAGGTGGCTGATTTAACGCATGCAATGGAAAATGTACT
AGATGAGGTACGCAATAATCGATTGGCTGTAACAGAACATTTGGTAGACATTATTTTTACATGTACATCT
CATTTAGAAACAATGGTTTCGGATATCCAGCACGGCGGACAAGGCGCGGCGGACATTTCGAAAACCGTAG
CTGACTTAGAAGCACTTTTACACCCAGAGCAAGAAACTGATTTAACGGTAGAAAAAACTTACCGTATTGC
CATTCAAATTGAAGAAGCAGCCATTTTGAAAGCAGTGCGGGCGGTAATGTGTTTAGAGCGACTTGCGGAA
ATGGGGATTATTTCAGAAACGACGCCAGACAGAGAAGCGATTGAGCTAGAAGAGTTTGAGCAGTCATTTG
AAGTAGTCCTAGAGTCGGCGCAAACGAAAGACGAAATCAAAGCGGTTATTCTGGATATTTCTGAAATCGA
AAAAGTGACTGTGACAGAAGAAGTGGAAGAAGTTCAGGTTATTGAACCAATCAAAAAAGCCGCAAAACAA
ACAACCAAACGATTAGAAAATAAAACCATTCGTGTACAACTTGAAAAAATCGAAAAGCTAATGAACGTTT
TTGAAGAAAGCGTCATTGAACGGGCGAGAATTGATGAAATCGCAGAAAAAACCAATAACAAAGAATTGAT
GGAACACTTAGGACGATTCAGTTCCATCTCCAAAGAAATTCAAAACGGCTTACTAAATATGCGTATGGTG
CCAGTGGACAGTGTGTTCAATCGCTTTCCAAAAATGGTGCGCACGCTAGCCAAAGAATTAGGCAAGAAAA
TCGATTTAGTGATTGAAGGCGCAGATACGGAAGTCGATAAAATCGTCATTGATGAAATTGGTGACCCACT
TGTTCACTTAATCCGTAATTCGGTAGATCACGGCGCTGAAACAGTCGAAGTGAGACGTAAAAACGGGAAA
AATGAAACCGCCACAATTAATCTAAAAGCTTTCCATAGCGGGAACAATGTCGTTATCGAAATTGCGGATG
ACGGTGCGGGAATCAATAAACGCAAAGTGTTAGAAAAAGCAATTGCGAAAAATGTTGTTACAAGAGCAGA
ATCAACGAAAATGACTGACGCGGAAATTTTTGATTTATTATTTGATTCCGGTTTCAGTACCGCAGATCAA
GTATCAGATCTTTCCGGTCGCGGCGTTGGCTTAGACGTAGTCCGTAACACCATTCTTAAAATCGGCGGGA
AAATCAGCGTAGAATCAAGTGAAAACGCTGGTTCGACGTTCCGAATTGAGATTCCGCTGACATTATCAAT
CATCCAGTCGATGCTCGTTGCAACATCTGAACGCCGCTATGCTGTACCGCTGGCAAACGTGGCCGAAGCT
ATCACAATTAATCCAGCGGACATTCAACACGTTCACGGCAAAGACTTAATCAACTACCGTGAAACGATTA
TTGAAGTACTCGATTTAGGTGAATGCTTCCATGAAACACCTTTGAATGACACGGATGAATTACTATTGCT
CGTCGTGAAAAATGCCAAGCGTACTTTTGGACTTATTATTAAAGATATTATCGGTCAACGGGAAATTGTT
TTAAAAACACTTGGCGGCTTTTTCAGCGAAAGTCAAATTGCCTTTTCTGGGGCAACGATTTTAGGCGATG
GCCGTGTCGTATTAATTTTAAATTTAGAAACATTTTA
Protein Sequence 
>gi|16802734|ref|NP_464219.1| two-component sensor histidine kinase CheA [Listeria monocytogenes EGD-e]
MTTNMLDLFIEEASEHLQALNDNLLQLEKDPTNGQLVSEIFRSAHTFKGMSATMGFQQVADLTHAMENVL
DEVRNNRLAVTEHLVDIIFTCTSHLETMVSDIQHGGQGAADISKTVADLEALLHPEQETDLTVEKTYRIA
IQIEEAAILKAVRAVMCLERLAEMGIISETTPDREAIELEEFEQSFEVVLESAQTKDEIKAVILDISEIE
KVTVTEEVEEVQVIEPIKKAAKQTTKRLENKTIRVQLEKIEKLMNVFEESVIERARIDEIAEKTNNKELM
EHLGRFSSISKEIQNGLLNMRMVPVDSVFNRFPKMVRTLAKELGKKIDLVIEGADTEVDKIVIDEIGDPL
VHLIRNSVDHGAETVEVRRKNGKNETATINLKAFHSGNNVVIEIADDGAGINKRKVLEKAIAKNVVTRAE
STKMTDAEIFDLLFDSGFSTADQVSDLSGRGVGLDVVRNTILKIGGKISVESSENAGSTFRIEIPLTLSI
IQSMLVATSERRYAVPLANVAEAITINPADIQHVHGKDLINYRETIIEVLDLGECFHETPLNDTDELLLL
VVKNAKRTFGLIIKDIIGQREIVLKTLGGFFSESQIAFSGATILGDGRVVLILNLETF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant reduced invasion of Caco-2 cells compared to wild type (Dons et al., 2004).
COG COG0643NT, under N: Cell motility; T: Signal transduction mechanisms
References
Dons et al., 2004: Dons L, Eriksson E, Jin Y, Rottenberg ME, Kristensson K, Larsen CN, Bresciani J, Olsen JE. Role of flagellin and the two-component CheA/CheY system of Listeria monocytogenes in host cell invasion and virulence. Infection and immunity. 2004; 72(6); 3237-3244. [PubMed: 15155625].