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surA

Victor ID 5007
Gene Name surA
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1251610
NCBI Protein GI 16763482
Locus Tag STM0092
Genbank Accession AE006468
Protein Accession NP_459097
Taxonomy ID 700720
Gene Starting Position 104469
Gene Ending Position 105755
Gene Strand (Orientation) -
Protein Name peptidyl-prolyl cis-trans isomerase SurA
Protein pI 7.32
Protein Weight 44868.68
Protein Length 428
Protein Note Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB
DNA Sequence 
>gi|16763390:104469-105755 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
ATTAGTTACTCAAAATCTTAACGTAAGCGCTGGCGCGCTGTTCTTGCATCCAGGTCGCCGCTTCTTCTGA
GAATTTACGGTTCATCAGCATACGATAAGCGCGATCTTTCTGCGCCGCATCGGTTTTGTCTACCTTACGC
GTATCCAGCAATTCGATCAGATGCCAGCCGAAAGAGGAGTGTACCGGCGCGCTTATTTGGCCTTTATGCA
GCTTCGTTAGCGCGTCGCGGAACGCCGGGTCGAAAATATCTGGCGTAGCCCAACCCAAATCACCGCCCTG
GTTAGCGGAGCCCGGGTCCTGAGAGTACTCTTTCGCCGCAGCGGCAAAGGTGGTTTTACCACTCTTAATG
TCAGCCGCGATTTCTTCCAGCTTCAGGCGCGCCTGCTGATCGTTCATGATCGGCGACGGCTTAAGCAGAA
TGTGACGAGCGTGAACTTCGGTCACGGAGATACTCTGGCTCTGACCGCGCAGGTCATTTACTTTCAGAAT
GTGGAAGCCGACGCCGGAGCGAATCGGGCCGACAATGTCGCCTTTCTTCGCGGTGCTCAGCGCCTGGGCG
AAAATCCCCGGCAGCTCCTGGATACGGCCCCAGCCCATCTGACCGCCTTTTAGCGCCTGCTGGTCGGCAG
AGTAGGTAATCGCCAGTTTGCCGAAATCTGCGCCGTTACGCGCTTCTTCAACAATGCTTTCCGCCTGGCG
CTGCGCGTCGTTAACCTGCTCGGAGGTTGGGTTTTCCGGCAGAGCAATCAGGATATGGCTCAGGTTCAGC
TCGGTGCTGGCATCGTTTTGGGTGCCAATCTGTTTTGCCAGCGCGTCAACTTCTTGCGGCAAAACGGTGA
TACGGCGACGAACCTCATTGTTGCGCACTTCAGAGATAATCATCTCTTTACGAATCTGGTTACGGTAGGT
TGAATAGTTCAGCCCATCGTAAGCCAGACGGCTGCGCATCTGATCCATCGTCATATTGTTTTGTTTGGCG
ATGTTGGCGATGGCCTGATCCAACTGCTCATCCGTGATCTTCACCCCCATCTTCTGACCCATCTGCAGGA
TAATTTGATCCATAATCAAACGTTCCAGGATCTGGTGACGCAGCGTGGCGTCGTCCGGAAGCTGCTGACC
TGCCTGACCCGCGTTGAGTTTGACTGATTGCATTAAGCCATCAACGTCGCTTTCCAGCACGACGCCATTA
TTGACGACGGCTGCGACTTTATCGACTACCTGGGGGGCAGCGAAACTGGTATTCGCGATCATGGCGATAC
CGAGAAGCAGCGTTTTCCAGTTCTTCA
Protein Sequence 
>gi|16763482|ref|NP_459097.1| peptidyl-prolyl cis-trans isomerase SurA [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQI
LERLIMDQIILQMGQKMGVKITDEQLDQAIANIAKQNNMTMDQMRSRLAYDGLNYSTYRNQIRKEMIISE
VRNNEVRRRITVLPQEVDALAKQIGTQNDASTELNLSHILIALPENPTSEQVNDAQRQAESIVEEARNGA
DFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGQSQSI
SVTEVHARHILLKPSPIMNDQQARLKLEEIAADIKSGKTTFAAAAKEYSQDPGSANQGGDLGWATPDIFD
PAFRDALTKLHKGQISAPVHSSFGWHLIELLDTRKVDKTDAAQKDRAYRMLMNRKFSEEAATWMQEQRAS
AYVKILSN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A surA mutant (BRD1115) is attenuated in BALB/c mice (Sydenham et al., 2000).
COG COG0760O, under O: Posttranslational modification, protein turnover, chaperones
References
Sydenham et al., 2000: Sydenham M, Douce G, Bowe F, Ahmed S, Chatfield S, Dougan G. Salmonella enterica serovar typhimurium surA mutants are attenuated and effective live oral vaccines. Infection and immunity. 2000; 68(3); 1109-1115. [PubMed: 10678914].