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yjeA

Victor ID 5005
Gene Name yjeA
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1255870
NCBI Protein GI 16767593
Locus Tag STM4344
Genbank Accession AE006468
Protein Accession NP_463208
Taxonomy ID 700720
Gene Starting Position 4586094
Gene Ending Position 4587071
Gene Strand (Orientation) +
Protein Name lysyl-tRNA synthetase
Protein pI 4.92
Protein Weight 35366.49
Protein Length 325
Protein Note lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
DNA Sequence 
>gi|16763390:4586094-4587071 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
CATGAGCGAAACGGCAACCTGGCAGCCGAGCGCGTCCATCCCCAATTTATTAAAACGTGCGGCGATTATG
GCGGAAATCCGTCGTTTCTTTGCCGATCGTGGAGTGCTTGAGGTTGAGACGCCCTGCATGAGTCAGGCGA
CGGTCACAGACATTCATCTGTTCCCGTTCGAAACGCGTTTCGTCGGACCTGGCCATTCCCAGGGGATCAA
CCTCTATTTAATGACCAGTCCGGAATACCATATGAAACGCCTGCTGGCGGCAGGGTGCGGCCCGGTTTTC
CAGCTATGCCGCAGTTTCCGTAATGAAGAGATGGGACGACATCATAATCCGGAATTCACTATGCTGGAGT
GGTATCGCCCGCATTACGATATGTACCGCCTGATGAATGAAGTGGATGATTTGCTTCAGCAAGTGCTGGA
TTGTCAACCTGCGGAAAGTCTCTCCTATCAACAGGCGTTTCAGCGCCATCTGGAGATTGACCCGTTATCA
GCAGATAAAACGCAACTGCGTGAGGCGGCGGCAAAGCTTGATTTAAGCAATATCGCCGATACGGAAGAAG
ACCGTGATACGTTGCTGCAACTGTTGTTCACGATGGGGGTTGAGCCGCATATAGGTAAAGAAAAGCCGAC
CTTTATTTATCACTTTCCGGCAAGTCAGGCATCGCTGGCACAAATCAGTACCGAGGATCATCGCGTCGCC
GAGCGCTTTGAGGTGTACTACAAAGGTATTGAGCTGGCGAATGGTTTCCACGAACTGACGGACGCACGTG
AGCAACAACAGCGCTTTGAACAGGACAATCGTAAGCGCGCCGCTCGCGGTCTGCCGCAGCAGCCGATTGA
CCAAAATCTACTGGATGCGCTGGCCGCCGGTCTACCGGATTGTTCCGGCGTGGCGCTGGGTGTTGATCGT
CTGGTGATGCTGGCGCTGGGAGCAGAAAGCCTGGCGGACGTGATTGCTTTTACGGTCGATCGGGCGTA
Protein Sequence 
>gi|16767593|ref|NP_463208.1| lysyl-tRNA synthetase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
MSETATWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLFPFETRFVGPGHSQGIN
LYLMTSPEYHMKRLLAAGCGPVFQLCRSFRNEEMGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLD
CQPAESLSYQQAFQRHLEIDPLSADKTQLREAAAKLDLSNIADTEEDRDTLLQLLFTMGVEPHIGKEKPT
FIYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQQPID
QNLLDALAAGLPDCSGVALGVDRLVMLALGAESLADVIAFTVDRA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A poxA mutant is attenuated in mice (Kaniga et al., 1998).
COG COG2269J, under J: Translation, ribosomal structure and biogenesis
References
Kaniga et al., 1998: Kaniga K, Compton MS, Curtiss R 3rd, Sundaram P. Molecular and functional characterization of Salmonella enterica serovar typhimurium poxA gene: effect on attenuation of virulence and protection. Infection and immunity. 1998; 66(12); 5599-5606. [PubMed: 9826331].