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UIS3

Victor ID 4991
Gene Name UIS3
Sequence Strain (Species/Organism) Plasmodium yoelii yoelii str. 17XNL
NCBI Gene ID 3830198
NCBI Protein GI 83315853
Locus Tag PY03011
Genbank Accession AABL01000850
Protein Accession XP_730972
Taxonomy ID 352914
Gene Starting Position 1385
Gene Ending Position 2296
Gene Strand (Orientation) -
Protein pI 9.63
Protein Weight 26806.7
Protein Length 241
DNA Sequence 
>gi|221228555:1385-2296 Plasmodium yoelii yoelii str. 17XNL MALPY00853, whole genome shotgun sequence
TTCATTTTGGTTGATATTGTTCTTTAAGAAAATGCTCCACGCCTAAAACTGCGATATCTTCTTGGGCTCT
TGAAATATTAACATCCTTATTTTCATCTAAAGTCTGGACAATTTTCCTTAAGTAATCATAATCCTTGATT
AAATATTTCTGTTGTTCATTTGATAAATTGCTGAAATGGTGTTTAGCAGCTAGTTTCACATTATCCATAA
ATGTATTAAACCTTTTCAAAGGAACATCAATATCATTATTGTTTTCTTTTAATTTTCCTTTTATATTTAC
TTTATTTACTCCTAATGGTTCTTCATATTTTGTACTAGTGCTTGGTTTTTCACCATCAGGTTGTTTATAT
TCTGTTTGTTTATTAAAGGGGAAAAAATTAAAACCTTTATTCCAATCATGTCTTCCTTTATTATGAGATT
TATACATATAATAAAGTACCCCAATAACACTTGCCACTAATCCTGATGATAACAAAGCAATTGCAACTGA
TTTCCTCTTCTTTTTTTTTTTTATAGCAGTATCAATGCTATCTAATGCCCCATCATCTATTTCTGAATAA
TAATCTGCATCCTCACAAAAGCAAGGGTTAAAAAAAAATGTAGTAATATATAACACATAAAAAACGAAAA
AAACTTTGAGAGTGTTCATTTTATACACTTTCATATATTTTTTATTTGTCTAAGTAATAAAAAAAATTAA
ATTACTATAAAGATCAAATAATTATGTACAAATTTTTATCATTATTATTGTTAATATTATATTTTTTTTT
TATGTGTCAACAAAAAATTATTAAGCAAAGAATAATCTTTGAGTCACAATGATAAATGTGATGCTATTAT
AAATAATATTTCCTGTCAATCATACTCTAAAATATTTATTAATATAAATTATGCATGTGAAAAATTGAGG
CA
Protein Sequence 
>gi|83315853|ref|XP_730972.1| early transcribed membrane protein [Plasmodium yoelii yoelii str. 17XNL]
MPQFFTCIIYINKYFRTNKKYMKVYKMNTLKVFFVFYVLYITTFFFNPCFCEDADYYSEIDDGALDSIDT
AIKKKKKRKSVAIALLSSGLVASVIGVLYYMYKSHNKGRHDWNKGFNFFPFNKQTEYKQPDGEKPSTSTK
YEEPLGVNKVNIKGKLKENNNDIDVPLKRFNTFMDNVKLAAKHHFSNLSNEQQKYLIKDYDYLRKIVQTL
DENKDVNISRAQEDIAVLGVEHFLKEQYQPK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Deletion of UIS3 in Plasmodium yoelii provided attenuation and full protection in mice (Tarun et al., 2007).
References
Tarun et al., 2007: Tarun AS, Dumpit RF, Camargo N, Labaied M, Liu P, Takagi A, Wang R, Kappe SH. Protracted sterile protection with Plasmodium yoelii pre-erythrocytic genetically attenuated parasite malaria vaccines is independent of significant liver-stage persistence and is mediated by CD8+ T cells. The Journal of infectious diseases. 2007; 196(4); 608-616. [PubMed: 17624848].