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Py52

Victor ID 4990
Gene Name Py52
Sequence Strain (Species/Organism) Plasmodium yoelii 17XNL
NCBI Nucleotide GI 15193061
NCBI Protein GI 15193062
Protein Accession AAK91678.1
Taxonomy ID 5861
Gene Strand (Orientation) ?
Protein Name Py52
Protein Note member of the 6 cysteine family of Plasmodium proteins; putative membrane-bound protein; sporozoite expressed
DNA Sequence 
>gi|15193061|gb|AF390552.1| Plasmodium yoelii Py52 mRNA, complete cds
ATGAAACGTCGAAGCATTTTCATGTACTACTGTTTCTGTTTCTTATTGAAATATGTAGCCTTTAGCAATG
TGCCAAATCCTAATACGACCATAGGACACTTTGAAATTTGTGAAGTAAATACATCTTCAGGTGATGCCGA
AGAATGTGTTTTAGAAAATGAATTTGGGAAAATGTTTTTATTTATTTGTGATATTGATTACAATGAGATG
TCAAAAAATATAGTGCTTCCGTCAGAATGTGCTAAAAAAACATATATAGACCATGTAAACCCAAATGGAA
CATCGCCAGAAGTTAATACTTATGATATATTTCCAGATTTGATCGCAGCAAATGAATCCCAATTTCGTGA
TAAATTTTATTTTTATGGAACCCCATATTCATCTAAAGACATTGATTTTATATGTTTATGTTTTTCTGAA
ACAAAACCAGATATAAAACATGTAATGAAAATGAGTTTTAAAAAAATGACAAAAAAAATAAAAGGATGTG
ATTTTGGAGATAATATACCAACGAAAAAAGATTTAACAAATGGGAAAGCATTATATGAAAATTCTAGTTG
TCATATATATGCATATCCAGGAGACGTAATTGGAATAAATTGTTATAAAAAAGACATTAATAATATTTAT
AATAATAATTTAGAATTACAGCCAAATAATTGTTTTCATAATGTTTATTATGAAGATGATATATTATTAT
CGTCAAAAAATTTAATACCTAATTCTAGAGTTATACCAGATCCGAGTAACGATGTTAAATTATCAAAAAT
GCATTCATATATGTCTTATATTATACTCCCTGACGAAATAAATGAAAATGTTAAAATTAGTTGTGCATGC
AAAAGAGATGAATATATCGGCACTATGTTTTTATATGTAAATACATCGAAAAATATTTTAACATCCCCTG
ACAACAACGTAGAAGAAATTGCTCCTTTGAATGACCACTATATTTCAATTGGAGACATGTGGGACATGGG
TTTACATGAAAACCCTGAGCAAATACAAGGCATTATTAGCAATCATGCAAATAAAAAATATTATGAACAT
ATGAAAATTTACAAAAGCAATAAAATGGATTCTAGTGATGATGATGAATCGAATGAGACTGAATCGAGTG
AGAATGAATCAAATGAGCGCACACACAATGGTAATAGAGCAAATAAAGATGCTAATAATAGTGAGAAAAT
GACTGGTAATAGAAGGAAAAAAAATAATTCTATCAATAATACTAATTACTATAGTAATTATGAGGATGAC
AATGGAATTAATATATCTACCCATGATAAATATTATGAGGACCAACATTTTGGTAACAATGGACCTTTGA
GAAAGAAAAGAACATTTTGGCAAAATATGTTTGGTACCTCTTCTTCTTATTATGAGGTCTTTAACTATTT
TTCAATCGCATTTATTCTAATTATTCATATGCTCCTCTTATGA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice (Labaied et al., 2007).
References
Labaied et al., 2007: Labaied M, Harupa A, Dumpit RF, Coppens I, Mikolajczak SA, Kappe SH. Plasmodium yoelii sporozoites with simultaneous deletion of P52 and P36 are completely attenuated and confer sterile immunity against infection. Infection and immunity. 2007; 75(8); 3758-3768. [PubMed: 17517871].