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FabB/FabF

Victor ID 4987
Gene Name FabB/FabF
Sequence Strain (Species/Organism) Plasmodium falciparum 3D7
NCBI Gene ID 3885996
NCBI Protein GI 296004726
Locus Tag PFF1275c
Genbank Accession AL844505
Protein Accession XP_966246
Taxonomy ID 36329
Chromosome No 6
Gene Starting Position 1061115
Gene Ending Position 1062891
Gene Strand (Orientation) -
Protein pI 9.25
Protein Weight 50967.34
Protein Length 473
DNA Sequence 
>gi|86176855:1061115-1062891 Plasmodium falciparum 3D7 chromosome 6
ATCACTTTACAATTTTTTTGAAAAGTAATGCTGTGTTATGGCCTCCAAATCCCAAATTTGTATTGAGAGA
TATATCAATATTTTCCTTTGCATGAATATATTTATTAGGTGTATAATTTAGATCACAATCTGGGTCCTTA
TATTCATAATTAATAGTAGGTGGTATAATATTTGTTTGCATAGTTTTAAGACATACAATAGATTCTATAG
CTCCAGCAGCACCTATACAATGTCCTGTCATACTTTTAGTTGATGATATATATAATTTGTATGCATGATC
TTTGAAAACATTTTTAAAAACCTTGGTTTCTATTTTATCATTTAAATTTGTTGAAGTACCATGTGCATTA
ATATATTTAACGTCATTTATGTTTATATTTGCATTTTTTAATGCTTTATGAATAGAATTTGTTAAACCTT
TCCCATTAGGTTCTGGTGCAGTAATATGGTATGCATCACATTCTGAAGAATATGAAATAATTTCTCCATA
TATTGGTGCATTTCTTTTTATTGCATGTTCGTATGATTCTAGAATTAAGATGCCTGAACCTTCTCCCATA
ACGAAACCACTTCTTTTTAAATCGAAGGGTCTACAACCTTTTTTTGGATTATCGTTATAACCTGTACATA
AAGCCTTTAATGAATTGAATCCAGCAAAACTTATAGGAGTTATACTAGCTTCAGTTCCACCACATATCAT
AACATCATACTCTTTATATTTTATATATCTATAGGCTTCACCTATTGTGTTACCAGACGTAGCACATGCA
CTTAACATACCAAGAGAGATCCCTCTAATATTGTTTTCGATAGATACATATCCAGATGGAGTATTTGCTA
TCATTGCAGGTATTAAATATGGTGTTATTCTTTTATGTCCTTTTTCATACATTGTTTTCATTTCTTTTTC
TAAAAATCTTAGTCCACCTATGCCACTACCTATGATAGTACCTGTTTTATCTTTGTCTAATTTTTCCAAA
TTTAGTTTTGCATCGTCTAAAGCTAAACGTGTGGCTGCGACTGCATAATGAGTACAATCATCATTACGAT
TAACATCTTTTTTATTTGTGTAATAATCACTAGGATTAAAATCGCTTTTCTTTATTTCACTACCAATACC
ACATGACATACCGGTTATATCAAATTTTGTAATTTTATCTATTGATGTATATCCATTTATAATATTATTC
CAAAAATGTTCTATGCCAATCCCTAATCCAGTTACTACCCCTACACCTGTGCACACCACTCTAGAAGTCT
AAATAAAAAATAAAAGAATTAAGAAAATTAAAATATATATAAAAATAAATGTATAGCATATTATTACTTT
AATCATTTTTTACAATTTGTATATATCACATTTTATAAAACTATATAAATATAAATATATATATATATAT
ATATATATATTATATATATTATATATTTTATTTAGTACTTCACAAAGATTTTTCATTTCTCTCGAATTGT
ACAACTTGAAACCTTTAAAATAATTCTTGGATATTCCAGGTATACCCCTTTTAATGAAGGCATACCTTTT
ACTGTTAACCTACATATGAAAATACATGGAGTATATATTATGACATGATTAATGTTTTTTTTTTTTTTTT
TTTTTTTTTCTTTTCTACATCTAATATTCATATGGCACATGCATATGTTTGAAAGGGGAAACATATATTA
ACTATTATGTTTGTTTTATTTTATTTTTAGAATTGTAGCATTACTTGTAGCACATAAAAGAACAGGAAAT
AATATATTTTTATAATGTATTTTCTCA
Protein Sequence 
>gi|296004726|ref|XP_966246.2| 3-oxoacyl-acyl-carrier protein synthase I/II [Plasmodium falciparum 3D7]
MRKYIIKIYYFLFFYVLQVNSKRYAFIKRGIPGISKNYFKGFKLYNSREMKNLCETSRVVCTGVGVVTGL
GIGIEHFWNNIINGYTSIDKITKFDITGMSCGIGSEIKKSDFNPSDYYTNKKDVNRNDDCTHYAVAATRL
ALDDAKLNLEKLDKDKTGTIIGSGIGGLRFLEKEMKTMYEKGHKRITPYLIPAMIANTPSGYVSIENNIR
GISLGMLSACATSGNTIGEAYRYIKYKEYDVMICGGTEASITPISFAGFNSLKALCTGYNDNPKKGCRPF
DLKRSGFVMGEGSGILILESYEHAIKRNAPIYGEIISYSSECDAYHITAPEPNGKGLTNSIHKALKNANI
NINDVKYINAHGTSTNLNDKIETKVFKNVFKDHAYKLYISSTKSMTGHCIGAAGAIESIVCLKTMQTNII
PPTINYEYKDPDCDLNYTPNKYIHAKENIDISLNTNLGFGGHNTALLFKKIVK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A genetically attenuated parasite (GAP) with a mutation in the FabB/FabF gene is attenuated in mice by arresting in the late liver stage (Butler et al., 2011).
References
Butler et al., 2011: Butler NS, Schmidt NW, Vaughan AM, Aly AS, Kappe SH, Harty JT. Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites. Cell host & microbe. 2011; 9(6); 451-462. [PubMed: 21669394].