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relA

Victor ID 4985
Gene Name relA
Sequence Strain (Species/Organism) Mycobacterium avium subsp. paratuberculosis K-10
NCBI Gene ID 2717869
NCBI Protein GI 41407145
Locus Tag MAP1047
Genbank Accession AE016958
Protein Accession NP_959981
Taxonomy ID 262316
Gene Starting Position 1095829
Gene Ending Position 1098195
Gene Strand (Orientation) +
Protein Name RelA
Protein pI 7.63
Protein Weight 79917.73
Protein Length 788
DNA Sequence 
>gi|41406098:1095829-1098195 Mycobacterium avium subsp. paratuberculosis K-10, complete genome
CGTGGCGGAGGAAAACAGCGCGGCGCAAGCGCTTGACGCGCCGGCGGAGTCGCCGCCCAACCCGGTGATC
GAGACTCCCGAGCCGCCGACCGAATCGCTCAAGACGTCCAGCAGCGCGTCGCGCCGGGTCCGGGCCCGGC
TGGCCCGGCGGATGACCGCCCAGCGCAGCACGCTCAACCCGGTGCTGGAGCCGCTGGTGGCGATGCACCG
CGAGATCTACCCCAAGGCCAACGTGCAGCTGCTGCAGCGCGCATTCGAGGTCGCCGACCAGCGGCACGCC
AGCCAGTTGCGCCACTCCGGCGACCCCTACATCACCCATCCGCTGGCCGTCGCCACCATCCTGGCCGAAT
TGGGCATGGACACCACCACTTTGGTGGCCGCGCTGTTGCACGACACCGTCGAGGACACCGGCTACACCCT
GGCCCAGCTGTCCGAGGAATTCGGCGAAGAGGTCGGTCATCTGGTCGACGGGGTGACCAAGCTGGACCGG
GTGGTGCTGGGCAGCGCCGCCGAGGGCGAGACCATCCGCAAGATGATCACCGCGATGGCCCGCGACCCGC
GGGTGCTGGTGATCAAGGTCGCCGACCGGCTGCACAACATGCGCACCATGCGGTTCCTGCCGCCGGAGAA
GCAGGCCCGCAAGGCCCGCGAGACGCTGGAAGTCATTGCGCCCCTCGCCCATCGGCTGGGCATGGCCAGC
GTCAAGTGGGAGTTGGAGGACCTGTCGTTCGCCATCCTGCATCCCAAGAAGTACGACGAGATCGTCCGGC
TGGTCGCCGGCCGGGCCCCGTCGCGGGACACCTACCTGGCCAAGGTGCGGGCCGAGATCATCAACACGCT
GAACGCGTCGAAGATCAAGGCGACGGTGGAGGGCCGGCCCAAGCACTACTGGTCGATCTACCAGAAGATG
ATCGTCAAGGGCCGCGACTTCGACGACATCCACGACCTGGTCGGCATCCGCATCCTGTGCGACGAGATCC
GGGACTGCTATGCCGCTGTGGGCGTGGTGCATTCGCTGTGGCAGCCGATGGCCGGGCGGTTCAAGGACTA
CATCGCCCAGCCGCGCTACGGCGTCTACCAGTCGCTGCACACCACCGTCGTCGGGCCGGAGGGCAAGCCG
CTGGAGGTGCAGATCCGCACCCGCGACATGCACCGCACCGCCGAGTACGGCATCGCCGCGCACTGGCGCT
ACAAGGAAGCCAAGGGCCGCAACGGCGTTCCGCACCCGCACGCCGCCGCCGAGATCGACGACATGGCCTG
GATGCGCCAGCTGCTCGACTGGCAGCGGGAAGCCGCCGACCCGGGCGAATTCCTCGAGTCGCTGCGCTAT
GACCTTGCGGTACAAGAGATCTTCGTGTTCACCCCCAAGGGCGACGTGATCACCCTGCCCACCGGGTCGA
CGCCGATCGACTTCGCCTATGCCGTGCACACCGAGGTCGGGCACCGCTGCATCGGCGCCCGGGTCAACGG
CCGGCTGGTGGCGCTGGAACGCAAGCTGGAAAACGGGGAAGTCGTCGAGGTTTTCACCTCCAAGGCGGCC
AACGCGGGCCCGTCGCGGGACTGGCAGCAGTTCGTGGTGTCGCCGCGGGCCAAGGCCAAGATCCGGCAGT
GGTTCGCCAAGGAGCGGCGCGAGGAGGCCCTGGAGGCCGGCAAGGACGCGATGGCCCGCGAGGTGCGCCG
CGGCGGACTTCCGTTGCAGCGCTTGGTCAATGCCGAATCCATGAGCGCGGTGGCCCGCGAACTGCACTAC
GCCGACGTGTCGGCCCTCTACACCGCGATCGGTGAGGGGCATGTGTCGGCCCGGCACGTGGTGCAGCGGC
TGCTGGCCGAGCTCGGCGGCATCGACCAGACCGAGGAGGACCTCGCCGAGCGGTCCACCCCGACCACCAT
GCTGCGCCGCCCGCGCAGCAGCGACGACGTCGGCGTGTCGGTGCCCGGCGCCCCGGGCGTGCTGACCAAG
CTGGCCAAATGCTGCACGCCGGTGCCTGGGGACCAGATCATGGGATTCGTCACCCGCGGCGGCGGGGTGA
GCGTGCACCGCACCGACTGCACCAACGCCGCCTCGCTGCAGCAGCAGTCCGAGCGCATCATCGAGGTGCA
CTGGGCGCCGTCGCCGTCGTCGGTGTTCCTGGTGGCCATTCAGGTCGAGGCGCTCGACCGGCACCGGCTG
TTGTCCGACGTCACCCGGGTGCTGGCCGACGAGAAGGTCAACATCCTGTCCGCGTCGGTCACCACCTCCG
GTGACCGGGTTGCCATCAGCCGCTTCACCTTTGAGATGGGCGACCCCAAGCACCTCGGCCACCTGCTCAA
CGTGGTGCGCAACGTCGAAGGCGTCTACGACGTCTACCGGGTGACCTCCGCCGCCTG
Protein Sequence 
>gi|41407145|ref|NP_959981.1| RelA [Mycobacterium avium subsp. paratuberculosis K-10]
MAEENSAAQALDAPAESPPNPVIETPEPPTESLKTSSSASRRVRARLARRMTAQRSTLNPVLEPLVAMHR
EIYPKANVQLLQRAFEVADQRHASQLRHSGDPYITHPLAVATILAELGMDTTTLVAALLHDTVEDTGYTL
AQLSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEK
QARKARETLEVIAPLAHRLGMASVKWELEDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIINTL
NASKIKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDY
IAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDDMAW
MRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPIDFAYAVHTEVGHRCIGARVNG
RLVALERKLENGEVVEVFTSKAANAGPSRDWQQFVVSPRAKAKIRQWFAKERREEALEAGKDAMAREVRR
GGLPLQRLVNAESMSAVARELHYADVSALYTAIGEGHVSARHVVQRLLAELGGIDQTEEDLAERSTPTTM
LRRPRSSDDVGVSVPGAPGVLTKLAKCCTPVPGDQIMGFVTRGGGVSVHRTDCTNAASLQQQSERIIEVH
WAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN
VVRNVEGVYDVYRVTSAA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A M. avium relA mutant is attenuated in calves and goats (Park et al., 2011).
References
Park et al., 2011: Park KT, Allen AJ, Bannantine JP, Seo KS, Hamilton MJ, Abdellrazeq GS, Rihan HM, Grimm A, Davis WC. Evaluation of two mutants of Mycobacterium avium subsp. paratuberculosis as candidates for a live attenuated vaccine for Johne's disease. Vaccine. 2011; 29(29-30); 4709-4719. [PubMed: 21565243].