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FTL0552

Victor ID 4972
Gene Name FTL0552
Sequence Strain (Species/Organism) Francisella tularensis subsp. holarctica LVS
NCBI Gene ID 3952730
NCBI Protein GI 89255956
Locus Tag FTL_0552
Genbank Accession AM233362
Protein Accession YP_513318
Taxonomy ID 376619
Gene Starting Position 534315
Gene Ending Position 535001
Gene Strand (Orientation) ?
Protein Name two-component response regulator
Protein pI 6.31
Protein Weight 23733.73
Protein Length 228
DNA Sequence 
>gi|89255449:534315-535001 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
TATGAGAATATTGTTGGCTGAAGATGATCTTCATTTGGGTGAAGGCTTATTAGAAGCTTTGCAAAAAGAG
GGTTTGATTGTAAATCTAGTTTCAGATGGTGAGGCAGCGCAAACTTTTATAGAATCTGGATTGTATGATA
TAGTCGTCTTAGATATTGGTATGCCAATAAAAACTGGTTTAGAAGTTCTAAGAAATATTAGAAATAGAGG
TATTAAAGTACCAATAATACTGTTGACTGCTAGAGATGGTTTAGAAGATAGAATTAAAGGTCTTGATCTT
GGTGCTGATGATTATCTAACTAAGCCATTTGAGTTAAAAGAGCTAGTAGCTAGAATTAAAGCTATTTCTC
GTCGTATTGATACTAGATCTGGTAAAAGTGTTAATGAAGAAATTAGATTTGGAGATTATAGTTTTAATCC
AAGCTCTGAAACGGTAACCAAAGATGGAGTTATTATTCCTGTTTCAAAAAAAGAGTTAGCGCTTTTAGCT
ATATTGGTACAAAATGCTGGTAGGGTAGTACCAAAGACACAGCTTTTAGAAGAAATATATTCTACTGATA
AGGAAATGGATACAAACACCCTAGAAGTACATATGCATAATTTAAGAAAGAAAATTAACATTCCTAATTT
TATACAGACTATTAGAGGTGTTGGTTACTTTGTACAAAAGGATAAAGTAATTAAGTA
Protein Sequence 
>gi|89255956|ref|YP_513318.1| two-component response regulator [Francisella tularensis subsp. holarctica LVS]
MRILLAEDDLHLGEGLLEALQKEGLIVNLVSDGEAAQTFIESGLYDIVVLDIGMPIKTGLEVLRNIRNRG
IKVPIILLTARDGLEDRIKGLDLGADDYLTKPFELKELVARIKAISRRIDTRSGKSVNEEIRFGDYSFNP
SSETVTKDGVIIPVSKKELALLAILVQNAGRVVPKTQLLEEIYSTDKEMDTNTLEVHMHNLRKKINIPNF
IQTIRGVGYFVQKDKVIK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A FTL0552 mutant in Francisella tularensis was attenuated in mice (Sammons-Jackson et al., 2008).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
Sammons-Jackson et al., 2008: Sammons-Jackson WL, McClelland K, Manch-Citron JN, Metzger DW, Bakshi CS, Garcia E, Rasley A, Anderson BE. Generation and characterization of an attenuated mutant in a response regulator gene of Francisella tularensis live vaccine strain (LVS). DNA and cell biology. 2008; 27(7); 387-403. [PubMed: 18613792].