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sodC

Victor ID 4970
Gene Name sodC
Sequence Strain (Species/Organism) Francisella tularensis subsp. holarctica FTNF002-00
NCBI Gene ID 5522867
NCBI Protein GI 156501771
Locus Tag FTA_0403
Genbank Accession CP000803
Protein Accession YP_001427836
Taxonomy ID 458234
Gene Starting Position 350894
Gene Ending Position 351451
Gene Strand (Orientation) +
Protein Name copper/zinc superoxide dismutase
Protein pI 5.61
Protein Weight 18894.63
Protein Length 185
Protein Note 1.15.1.1
DNA Sequence 
>gi|156501369:350894-351451 Francisella tularensis subsp. holarctica FTNF002-00 chromosome, complete genome
AATGACTGCTTTTTATAAATTATGTGGAATGAGTATGCTTTCACTTGTATTAGCAGACTGCACATTCTTG
TCAGCAAATAAGCCTTATGATCGCGACCATGATGGTGAGTTAATTGTACATATGAAAGATGTCAATACTC
ATAAAGAGGTTGGAACAATCACAATATCACCATATATTCATGATGGTAACCAAGAAGGGATGTTGATTAC
GCCACATTTATATAATTTACCTGCTAATACTACTCATGGCATGCATATCCATATCAATCCTAGTTGTGAA
GATAATGGTATCGCAGCAGGTGGGCATTGGGATCCAGATAATACGCAAAAGCACCTTGGCCCATACAATG
ATAATGGACATAAGGGCGATTTGCCTGTACTAGTTGTTAACGCAGATGGTACAGCAACTGAGCCTGTTGT
AGCGCCAAAGCTTAATTCTCTAGAAGAGCTAGCGGGTCATAGTTTGATGCTTCATGCGGGAGGCGATAAT
TACTCTGATAAGCCACAACCTCTAGGCGGAGGTGGTGCTAGAATGTGGTGTGGAGTTATAGCAGACTA
Protein Sequence 
>gi|156501771|ref|YP_001427836.1| copper/zinc superoxide dismutase [Francisella tularensis subsp. holarctica FTNF002-00]
MTAFYKLCGMSMLSLVLADCTFLSANKPYDRDHDGELIVHMKDVNTHKEVGTITISPYIHDGNQEGMLIT
PHLYNLPANTTHGMHIHINPSCEDNGIAAGGHWDPDNTQKHLGPYNDNGHKGDLPVLVVNADGTATEPVV
APKLNSLEELAGHSLMLHAGGDNYSDKPQPLGGGGARMWCGVIAD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A sodC mutant in Francisella tularensis subspecies holarctica was attenuated in mice (Melillo et al., 2009).
COG COG2032P, under P: Inorganic ion transport and metabolism
References
Melillo et al., 2009: Melillo AA, Mahawar M, Sellati TJ, Malik M, Metzger DW, Melendez JA, Bakshi CS. Identification of Francisella tularensis live vaccine strain CuZn superoxide dismutase as critical for resistance to extracellularly generated reactive oxygen species. Journal of bacteriology. 2009; 191(20); 6447-6456. [PubMed: 19684141].