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UL23

Victor ID 4953
Gene Name UL23
Sequence Strain (Species/Organism) Bovine herpesvirus 1
NCBI Gene ID 1487380
NCBI Protein GI 9629852
Locus Tag BoHV1_gp21
Genbank Accession Z78205
Protein Accession NP_045336
Taxonomy ID 10320
Gene Starting Position 63259
Gene Ending Position 67035
Gene Strand (Orientation) +
Protein Name thymidine kinase
Protein pI 6.75
Protein Weight 35103.27
Protein Length 359
Protein Note 2.7.1.21
DNA Sequence 
>gi|9629818:63259-67035 Bovine herpesvirus 1, complete genome
CATGGCCGAGCCCGCGCGCGCTCTCCGCGTCGTGCGTATCTACCTGGACGGCGCGCACGGGCTGGGAAAG
ACAACAACGGGCCGCGCGCTCGCGGCCGCTTCCACCGCTGGGGAGGGCGTGCTCTTTTTCCCGGAGCCGA
TGGCGTACTGGCGCACGATGTTTGGTACGGACGCCTTAAGTGGGATCCTCGCGGCGTCTGCGCGATGCGC
CGCAGCCTCGCACGGGAGCGCACGCGGCGCCGGCGGGCCGGCGCACCGCGCAGACGCGGACGCGGCGGGC
CTGGTTGCGTACTACCAGGCCAGGTTCGCGGCCCCGTACTTAATTTTGCACGCGCGCGTGTCCGCGCTGC
TGGCGCCGCCTGGGCCGGCGCCGGGCGGCACTGTGACCCTCGTGTTCGACCGCCACCCCGTGGCCGCGTG
CCTCTGCTACCCCTTCGCCCGCTACTGCCTCCGCGAGATCAACGCGGAAGATCTGCTCATGCTCGCGGCC
GCCATGCCCCCGGAAGCGCCCGGGGCCAACCTCGTCGTGTGCACCCTCCCCCCGGCCGAGCAACAGCGCC
GCCTGGCGGCGCGGGCCAGGCCCGGAGACCGCGCGGACGCGGGCTTTCTGGTCGCTGTGCGCAATGCTTA
CGCGCTCCTGGTGAACACGTGCGCTTTCCTGCGCGCGGGGGGCGCATGGCGCGACGGCTGGGACGCGCTG
GAGTGGGCGGACGCAAATGCATTGGCCGCGCTCGCAGACCCCAGTTGTGATGAATGCAAAATGGCGCCGG
CGCCGGCGCTGCGCGACACCCTGTTCGCGGCGCTCAAGTGCCGCGAGCTCTACCCGGGCGGCGGGACGGG
CTTGCCCGCGGTTCACGCCTGGGCGCTGGACGCCCTGGCCGGCCGCCTCGCCGCCCTCGAGGTGTTCGTG
CTGGACGTGTCCGCGGCGCCAGACGCGTGCGCGGCCGCCGTACTGGACATGCGGCCCGCCATGCAGGCCG
CTTGCGCGGACGGGGCGGCGGGCGCGACGCTGGCGACCCTGGCGCGTCAGTTCGCGCTAGAGATGGCGGG
GGAGGCCACGGCGGGCCCTAGGGGACTATAAAGCTGCCCCTGCGCTCGCTCGCTCGCTGCATTTGCGCCC
CGATCGCCTTACGGGGACTCGGCGCTCGGCGGATCCCCTCCCGGCCCCGCCGCGAAGCGAGCCGCCAGAC
AAAAAAATGCGGCGCCCGCTCTGCGCGGCGCTATTGGCAGCGGCTGTCCTCGCGCTCGCCGCGGGCGCCC
CCGCCGCCGCCCGCGGCGGCGCGGGGGGCCGAAGCAGGGAGCACAGAGACGCCCGATACGAAATCGAAGA
GTGGGAAATGGTGGTCGGAGCCGGGCCGGCCGTGCACACGTTCACCATCCGCTGCCTCGGGCCGCGGGGC
ATTGAGCGCGTGGCCCACATTGCAAACCTCAGCCGGCTGCTGGACGGGTACATAGCGGTCCACGTTGACG
TTGCGCGCACCTCTGGCCTGCGGGACACCATGTTTTTCCTGCCGCGCGCGGCCGTCGACAACGCTTCGGC
CGCTGACATTCCGGACACCCCGGCCGTACAGTCGCACCCGGGGCTCTTCGGGGCGGCCTTTTCCTGGAGC
TACTTGCAAACGCGCCACCTCGTAGACTACGACCTGGTGCCGAGCCGCCCCCTGCAGGACTGGTACTTTT
CGCAGGCGCGCGCCGAGAGCAACGCCGCGCGCCCGCCGCCCGCCCCGCGCGTCACACCAACGCCGGCGGG
GCGGGTGGCCGCTTTTGACATCAACGACGTGCTGGCCAGCGGCCCGGAGCACTTCTTTGTGCCTGTGCGA
GCGGACCGCAAGCGGCGCGAGCGCCACGTGGCGGATTTTGCCGCGGTGTGGCCCGTGTCCTACATCCCCG
CAGGACGGGCAGTGCTAAGCTGCGAGCGAGCCGCGGCTCGGCTGGCGGTGGGGCTCGGCTTCCTGAGCGT
CTCGGTGACGTCGCGGGACCTCCTGCCTCTGGAGTTTATGGTCGCGCCCGCGGACGCCAACGTGCGCATG
ATTACCGCCTTTAACGGGGGCGGCGCTTTTCCGCCACCCGGGCCCGCGGCCGGTCCGCAGCGGCGGGCCT
ACGTAATCGGCTACGGGAACTCGCGGCTGGACAGCCATATGTATCTGACCATGCGCGAGGTGGCGTCGTA
CGCGAACGAGCCCGCTGACTTTCGCGCGCACTTGACCGCCGCGCACCGGGAGGCTTTTTTGATGCTCCGG
GAGGCGGCAGCCGCGCGCCGCGGACCGAGCGCCGGCCCCGCGCCCAACGCTGCCTACCACGCGTACCGGG
TCGCGGCGCGGCTGGGACTCGCGCTCTCCGCGCTCACCGAGGGGGCGCTCGCGGACGGCTACGTGCTCGC
GGAGGAGCTAGTCGACCTTGACTACCACCTCAAGCTGCTGTCGCGCGTGCTGCTCGGCGCAGGGCTTGGC
TGCGCCGCCAACGGCCGCGTGCGCGCCCGCACCATCGCGCAGCTGGCCGTGCCCCGCGAGCTACGCCCGG
ACGCGTTCATCCCAGAGCCCGCCGGGGCGGCGCTCGAGAGCGTGGTGGCCCGCGGGCGCAAGCTGCGCGC
CGTGTACGCTTTTTCGGGTCCGGACGCTCCGCTAGCTGCGCGGCTGCTGGCCCACGGCGTGGTGTCGGAC
CTCTACGACGCCTTCCTGCGCGGCGAGCTGACGTGGGGGCCGCCCATGCGCCACGCGCTTTTTTTCGCCG
TCGCGGCGTCGGCGTTCCCCGCGGACGCCCAGGCGCTGGAGCTCGCGCGGGACGTGACGCGCAAGTGCAC
GGCTATGTGCACCGCCGGGCACGCCACGGCGGCCGCGCTGGACCTGGAGGAGGTATACGCGCACGTCGGC
GGCGGCGCCGGGGGCGACGCGGGCTTTGAGCTGCTGGATGCCTTCTCGCCGTGCATGGCCTCTTTCCGCC
TGGACTTGCTCGAGGAGGCGCACGTGCTGGACGTGCTCTCGGCCGTGCCCGCGCGGGCCGCGCTGGACGC
CTGGCTGGAGGCGCAGCCCGCGGCCGCCGCGCCGAACCTCAGCGCGGCGGCGCTCGGCATGCTGGGCCGG
GGAGGCCTCTTCGGCCCGGCGCACGCCGCCGCGCTCGCGCCCGAGCTCTTCGCGGCGCCCTGCGGCGGGT
GGGGCGCGGGCGCCGCCGTGGCGATCGTCCCCGTGGCGCCGAACGCTAGCTATGTCATCACGCGCGCACA
TCCGCGGCGCGGGCTGACGTACACCCTCCAGGGAATTGACGTCGCTAACCCCCTGCTGGTGACTTTTGTG
CGCGGCACGTCGTGCGTGTCGGCCAGCGGCGCGGTGGAGGCGCGCCGCCTTGCGGTCCCCGGCCCGCTGG
ACGCGTGCGCCTACTGCGGCAGCGTGTTCGTGCGATACTTGCCCTCGGGCGCGGTTATGGACATCGTGCT
CATTGCGGACAAGCGCACCGAGGTTGAGTTCTCGCGCGGCGCCAACTCTAGCATGCCCGTCTTCAACCCT
CGCCTCCACAGCGGGCGCTCCCGCGCCATGCTGCTGTTCCCCAACGGGACGGTCGTAAGCGTCCTGGCCT
TCGCCGGGCACGAAGCGCCGACGTTTTCGCCGGCGTACGTCTGGGCGTCGGTAGGCGGGGCGCTGGTCGC
GGGTACCACGATATACGCCATCGCGAAGATGCTGTGCAGCTCGGTCCCGCTCGCGCGCGGGTACTCGTCG
GTCCCGGTGTTTTAGCGCGCGCGTTGCCCTCCCCCCCTTCCCCCTTTTCACGTCTCCCCGCCAATAA
Protein Sequence 
>gi|9629852|ref|NP_045336.1| thymidine kinase [Bovine herpesvirus 1]
MAEPARALRVVRIYLDGAHGLGKTTTGRALAAASTAGEGVLFFPEPMAYWRTMFGTDALSGILAASARCA
AASHGSARGAGGPAHRADADAAGLVAYYQARFAAPYLILHARVSALLAPPGPAPGGTVTLVFDRHPVAAC
LCYPFARYCLREINAEDLLMLAAAMPPEAPGANLVVCTLPPAEQQRRLAARARPGDRADAGFLVAVRNAY
ALLVNTCAFLRAGGAWRDGWDALEWADANALAALADPSCDECKMAPAPALRDTLFAALKCRELYPGGGTG
LPAVHAWALDALAGRLAALEVFVLDVSAAPDACAAAVLDMRPAMQAACADGAAGATLATLARQFALEMAG
EATAGPRGL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A thymidine kinase-deficient mutant (B8-D53) showed no detectable thymidine kinase-inducing activity and was attenuated in calves (Kit et al., 1985).
References
Kit et al., 1985: Kit S, Qavi H, Gaines JD, Billingsley P, McConnell S. Thymidine kinase-negative bovine herpesvirus type 1 mutant is stable and highly attenuated in calves. Archives of virology. 1985; 86(1-2); 63-83. [PubMed: 2994602].