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aroA

Victor ID 4950
Gene Name aroA
Sequence Strain (Species/Organism) Bordetella pertussis
NCBI Protein GI 144037
Other Database IDs CDD:179423
CDD:30129
Taxonomy ID 520
Gene Strand (Orientation) ?
Protein Length 442
Protein Note 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Protein Sequence 
>gi|144037|gb|AAA22968.1| 5-enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) [Bordetella pertussis]
MSGLAYLDLPAARLARGEVALPGSKSISNRVLLLAALAEGSTEITGLLDSDDTRVMLAALRQLGVSVGEV
ADGCVTIEGVARFPTEQAELFLGNAGTAFRPLTAALALMGGDYRLSGVPRMHERPIGDLVDALRQFGAGI
EYLGQAGYPPLRIGGGSIRVDGPVRVEGSVSSQFLTALLMAAPVLARRSGQDITIEVVGELISKPYIEIT
LNLMARFGVSVRRDGWRAFTIARDAVYRGPGRMAIEGDASTASYFLALGAIGGGPVRVTGVGEDSIQGDV
AFAATLAAMGADVRYGPGWIETRGVRVAEGGRLKAFDADFNLIPDAAMTAATLALYADGPCRLRNIGSWR
VKETDRIHAMHTELEKLGAGVQSGADWLEVAPPEPGGWRDAHIGTWDDHRMAMCFLLAAFGPAAVRILDP
GCVSKTFPDYFDVYAGLLAARD
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: An aroA mutant is highly attenuated in mice (Roberts et al., 1990).
References
Roberts et al., 1990: Roberts M, Maskell D, Novotny P, Dougan G. Construction and characterization in vivo of Bordetella pertussis aroA mutants. Infection and immunity. 1990; 58(3); 732-739. [PubMed: 2407655].