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aroA

Victor ID 4945
Gene Name aroA
Sequence Strain (Species/Organism) Aeromonas hydrophila subsp. hydrophila ATCC 7966
NCBI Gene ID 4489425
NCBI Protein GI 117619998
Locus Tag AHA_1979
Genbank Accession CP000462
Protein Accession YP_856510
Taxonomy ID 7966
Gene Starting Position 2172700
Gene Ending Position 2174067
Gene Strand (Orientation) +
Protein Name 3-phosphoshikimate 1-carboxyvinyltransferase
Protein pI 7.25
Protein Weight 46562.74
Protein Length 455
Protein Note catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
DNA Sequence 
>gi|117617447:2172700-2174067 Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genome
TTTGTGCCACCCGCAGTCTTGCCGAGCAGGGCGCGGGCTGCTAACGTCCGGTCAGGTCATTTTTTTGAGA
TCGTACAGGAAGTCTATGAATTCGTTGCGTTTGGAACCTATTTCTCGTGTGGCCGGTGAGGTCAATCTGC
CCGGCTCCAAGAGCGTGTCCAACCGGGCCCTGCTGCTGGCAGCCCTGGCCCGTGGCACCACCCGGCTCAC
CAACCTGCTCGACAGCGATGACATTCGTCACATGCTGGCGGCGCTGACCCAGCTCGGGGTCAAGTACAAG
CTCTCCGCCGACAAGACCGAGTGCACCGTGCACGGTCTGGGTCGCAGCTTCGCGGTGAAGGAGCCGGTCA
ATCTGTTCCTCGGCAACGCAGGCACCGCCATGCGACCGCTGTGCGCCGCCCTGTGTCTGGGCTCCGGCGA
ATACACCCTGGGCGGGGAACCGCGCATGGAAGAGCGCCCCATCGGCCATCTGGTGGATGCTCTGCGCGAA
GCGGGCGCCCATATCCAGTACCTGAAGAAAGACGGTTATCCGCCGCTGGTGGTGGATGCCAAGGGGCTAT
GGGGCGGCGATGTGCACGTCGACGGCTCTGTCTCCAGCCAGTTCCTGACGGCGTTTTTGATGGCGGCGCC
GATGGCGGCGGGCGATACCCGCATCCACATCAAGGGGGAGCTGGTCTCCAAGCCCTACATCGACATCACC
CTGCACATCATGAAGCAGTTCGGGGTGGTCATCGAGCACGACAACTACAAGCTGTTCTACATCAAGGGCA
ACCAGAGCTACGTCAGCCCGGGTGACTTCCTGGTGGAAGGGGATGCCTCCAGCGCCTCCTACTTCCTCGC
GGCGGGCGCCATCAAGGGCAAGGTGCGGGTTACCGGCATCGGCAAGCACAGCATTCAGGGCGACATCCAC
TTCGCCGACGTGCTGGAGAAGATGGGCGCGCGCATCACCTGGGGCGATGACTTCATCGAGGCCGAGCAGG
CGCCGCTGCACGGCATCGACATGGACATGAACCACATCCCCGATGCGGCCATGACCATCGCCGTGGCCGC
GCTGTTCGCCGAGGGGCCCACCTCGATTCGCAACATCTACAACTGGCGGGTGAAGGAGACCGACCGCCTG
CACGCCATGGCGACCGAGCTGCGCAAGCTGGGCGTCGAGGTGGAGGAGGGGCGTGACTTCATCACCGTTA
CCCCGCCAGCGCAGCTCAAGCATGCGGCCATCGATACCTACAACGACCACCGCATCGCCATGTGCTTCTC
GCTGGTGGCGCTGTCCGATACCGCCGTCACCATCAATGATCCGGGTTGTACCTCCAAGACTTTCCCGGAC
TACTTCGACAAGCTGGCCAGCATCAGTCAGCGCGCGTG
Protein Sequence 
>gi|117619998|ref|YP_856510.1| 3-phosphoshikimate 1-carboxyvinyltransferase [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
MCHPQSCRAGRGLLTSGQVIFLRSYRKSMNSLRLEPISRVAGEVNLPGSKSVSNRALLLAALARGTTRLT
NLLDSDDIRHMLAALTQLGVKYKLSADKTECTVHGLGRSFAVKEPVNLFLGNAGTAMRPLCAALCLGSGE
YTLGGEPRMEERPIGHLVDALREAGAHIQYLKKDGYPPLVVDAKGLWGGDVHVDGSVSSQFLTAFLMAAP
MAAGDTRIHIKGELVSKPYIDITLHIMKQFGVVIEHDNYKLFYIKGNQSYVSPGDFLVEGDASSASYFLA
AGAIKGKVRVTGIGKHSIQGDIHFADVLEKMGARITWGDDFIEAEQAPLHGIDMDMNHIPDAAMTIAVAA
LFAEGPTSIRNIYNWRVKETDRLHAMATELRKLGVEVEEGRDFITVTPPAQLKHAAIDTYNDHRIAMCFS
LVALSDTAVTINDPGCTSKTFPDYFDKLASISQRA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: An A. hydrophila aroA mutant is highly attenuated in trout (Hernanz et al., 1998).
References
Hernanz et al., 1998: Hernanz Moral C, Flaño del Castillo E, López Fierro P, Villena Cortés A, Anguita Castillo J, Cascón Soriano A, Sánchez Salazar M, Razquín Peralta B, Naharro Carrasco G. Molecular characterization of the Aeromonas hydrophila aroA gene and potential use of an auxotrophic aroA mutant as a live attenuated vaccine. Infection and immunity. 1998; 66(5); 1813-1821. [PubMed: 9573055].