Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

aroA

Victor ID 4938
Gene Name aroA
Sequence Strain (Species/Organism) Yersinia enterocolitica subsp. enterocolitica 8081
NCBI Gene ID 4713234
NCBI Protein GI 123441850
Locus Tag YE1538
Genbank Accession AM286415
Protein Accession YP_001005833
Taxonomy ID 393305
Gene Starting Position 1726120
Gene Ending Position 1727406
Gene Strand (Orientation) +
Protein Name 3-phosphoshikimate 1-carboxyvinyltransferase
Protein pI 5.16
Protein Weight 43855.83
Protein Length 428
Protein Note catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
DNA Sequence 
>gi|123440403:1726120-1727406 Yersinia enterocolitica subsp. enterocolitica 8081, complete genome
CATGCTGGAATCCCTGACTTTACACCCCATTGCCCTGATTAATGGCACTGTTAATTTACCCGGTTCTAAA
AGTGTTTCTAACCGTGCACTTCTTCTGGCAGCGCTGGCCGAGGGGACAACTCAGCTGAATAACTTGTTAG
ACAGTGATGACATTCGCCATATGCTTAATGCTCTACAGGCATTGGGGGTGAAATATCGCCTGTCTGCTGA
TCGTACCCGCTGTGAGGTTGATGGATTGGGCGGCAAATTGGTTGCTGAACAGCCATTAGAATTGTTTTTG
GGTAATGCCGGCACGGCCATGCGCCCATTGGCTGCGGCACTGTGCCTGGGGAAAAATGACATTGTATTGA
CCGGCGAACCACGCATGAAAGAGCGGCCAATTGGTCATTTGGTTGATGCATTGCGTCAGGGCGGAGCACA
GATTGATTATCTGGAGCAAGAAAACTACCCGCCGTTGCGCATACGCGGGGGCTTTCGTGGCGGTAAACTC
ACCGTAGACGGCAGTGTTTCCAGTCAATTCCTCACGGCACTTTTGATGACCGCTCCCTTAGCTGAACAAG
ATACTGAAATTCAGATCCAAGGGGAGTTGGTGTCTAAGCCTTATATCGACATTACGTTGCATCTGATGAA
AGCCTTCGGTGTGGATGTCGTTCATGAAAATTATCAGATTTTTCATATTAAAGGCGGGCAGACTTACCGC
TCACCAGGTATCTATCTGGTTGAAGGTGATGCGTCTTCTGCATCTTATTTCCTCGCCGCAGCTGCTATCA
AAGGTGGAACAGTCCGCGTAACCGGCATTGGTAAACAAAGTGTACAAGGTGATACCAAGTTTGCTGATGT
ACTGGAGAAAATGGGCGCTAAAATCAGTTGGGGTGATGATTATATCGAGTGCAGCCGTGGTGAATTACAG
GGTATCGATATGGATATGAACCATATTCCTGATGCTGCAATGACCATTGCTACCACCGCACTGTTTGCCG
ACGGCCCGACTGTTATTCGTAATATCTATAACTGGCGAGTGAAGGAAACCGACCGCTTATCCGCGATGGC
GACTGAATTGAGAAAAGTGGGCGCGGAAGTGGAAGAGGGGCAAGACTACATTCGGGTGGTGCCCCCTGCG
CAGCTAATCGCAGCCGAAATAGGGACTTATAATGACCACCGCATGGCGATGTGTTTCTCGCTGGTGGCTT
TATCTGACACGCCGGTGACTATCCTTGATCCGAAATGTACCGCGAAAACATTCCCTGACTACTTTGAACA
ACTGGCCCGATTGAGCCAGATAGCCTA
Protein Sequence 
>gi|123441850|ref|YP_001005833.1| 3-phosphoshikimate 1-carboxyvinyltransferase [Yersinia enterocolitica subsp. enterocolitica 8081]
MLESLTLHPIALINGTVNLPGSKSVSNRALLLAALAEGTTQLNNLLDSDDIRHMLNALQALGVKYRLSAD
RTRCEVDGLGGKLVAEQPLELFLGNAGTAMRPLAAALCLGKNDIVLTGEPRMKERPIGHLVDALRQGGAQ
IDYLEQENYPPLRIRGGFRGGKLTVDGSVSSQFLTALLMTAPLAEQDTEIQIQGELVSKPYIDITLHLMK
AFGVDVVHENYQIFHIKGGQTYRSPGIYLVEGDASSASYFLAAAAIKGGTVRVTGIGKQSVQGDTKFADV
LEKMGAKISWGDDYIECSRGELQGIDMDMNHIPDAAMTIATTALFADGPTVIRNIYNWRVKETDRLSAMA
TELRKVGAEVEEGQDYIRVVPPAQLIAAEIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQ
LARLSQIA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: An aroA mutant is highly attenuated in mice (Bowe et al., 1989).
COG COG0128E, under E: Amino acid transport and metabolism
References
Bowe et al., 1989: Bowe F, O'Gaora P, Maskell D, Cafferkey M, Dougan G. Virulence, persistence, and immunogenicity of Yersinia enterocolitica O:8 aroA mutants. Infection and immunity. 1989; 57(10); 3234-3236. [PubMed: 2777382].