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aroA

Victor ID 4934
Gene Name aroA
Sequence Strain (Species/Organism) Staphylococcus aureus subsp. aureus ED98
NCBI Gene ID 8614197
NCBI Protein GI 269203089
Locus Tag SAAV_1451
Genbank Accession CP001781
Protein Accession YP_003282358
Taxonomy ID 681288
Gene Starting Position 1517365
Gene Ending Position 1518663
Gene Strand (Orientation) -
Protein Name 3-phosphoshikimate 1-carboxyvinyltransferase
Protein pI 4.84
Protein Weight 44289.51
Protein Length 432
DNA Sequence 
>gi|269201690:1517365-1518663 Staphylococcus aureus subsp. aureus ED98, complete genome
ATTATCCCTCATTTTCTAAAAGCTTTAGTTTTGGTAAAAATCCTGGAAATGATACATTTACAGCATCAAA
TTGTTTGATTTTGACAGGCTCGCTTGAAAGTAGAGAAGCAACTGCAAGCATCATTCCTATTCGATGATCA
GTTAAACTATCAACTGTTGCATTTGTTTTAAATTCTGACGGATGAATAATCAATCCATCATTAGTTGGTT
GTAATTCAAACCCTAACAAGTTTAACATATCAGCCGTTGTATCAATTCTATTTGTTTCTTTTACTTTTAA
TTCCTCGGCATCTTTAATTGTACTCGTGCCAACTGCTTGTGTACAAAGTAATGCTATTACAGGCAGTTCA
TCAATTGCTTTTGGAACTAATTCTCCTTCGATTGTTATTGGTTGAAGCATTGGTGTGTATTGAATACGAA
TAGAAGCAGTAGGTTCAGCACCAGTTGTTTGATTGAAAAGTTGGATATTACCGCCCATTTTTTCAACAAT
ATCAATAATACCTGAACGTGTTGGATTGATTCCAACATTATGAATTGTTACATCACTTTCTGGTGTGATA
AGTGCTGCAACAATAAAGAACGCTGCAGATGAAATATCGCCAGGAACATGAAAATCTGCAGGTTTAATAT
GTTGAATGGCATCAGGGGTTGTAGTTATTGATAACCTTTCTGCTTCAATTGGAATATTAAAATGTCTGAA
CATCGTCTCAGTATGATTTCGACTTACATCTAATTCCTTTATTACCGTTGTATCATTTGAAAACAAACTT
GCAAATAAAATGGCACTTTTTACTTGTGCACTTGCAACTTCCATTTGATAATTTATACCTTTTATGACAG
ATGGCTTAATAATTAATGGTGTATAATTATCTTCAATACCTTCAATATTCGCATCCATAAGTTTCAATGG
TCTCAAGACACGATCCATTGGCCTTTTACCAATTGAAACATCGCCAGACAAAACACTTTCAATACCTAAA
CCACTTAACAAACCAGCTAACAATCGAGTCGTTGTGCCAGAGTTTCCAGTATATAAAACTTGATGAGGTG
TTTTAAAAGCTTTATATCCAGGTGAATTCACAACCAATTTATCTTCATCTTCTTTAATATCTACGCCTAA
TAATCGGAATATATCCATTGTACGACGACAATCTTCACCAAGTAATGGTTTATAAATATTGGAAGTTCCT
TCAGCTAAAGATGCTAACATGATTGCTCGATGTGTCATCGACTTATCTCCAGGCACTTCTATTTCACCTT
TAAGTGGCCCTGAAATATCGATAATTTGTTCACTTACCA
Protein Sequence 
>gi|269203089|ref|YP_003282358.1| 3-phosphoshikimate 1-carboxyvinyltransferase [Staphylococcus aureus subsp. aureus ED98]
MVSEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGTSNIYKPLLGEDCRRTMDIFRLLGVDIKEDED
KLVVNSPGYKAFKTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSIGKRPMDRVLRPLKLMDANIE
GIEDNYTPLIIKPSVIKGINYQMEVASAQVKSAILFASLFSNDTTVIKELDVSRNHTETMFRHFNIPIEA
ERLSITTTPDAIQHIKPADFHVPGDISSAAFFIVAALITPESDVTIHNVGINPTRSGIIDIVEKMGGNIQ
LFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELPVIALLCTQAVGTSTIKDAEELKVKETNRID
TTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASLLSSEPVKIKQFDAVNVSFPG
FLPKLKLLENEG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: An aroA mutant is attenuated in mice (Buzzola et al., 2006).
COG COG0128E, under E: Amino acid transport and metabolism
References
Buzzola et al., 2006: Buzzola FR, Barbagelata MS, Caccuri RL, Sordelli DO. Attenuation and persistence of and ability to induce protective immunity to a Staphylococcus aureus aroA mutant in mice. Infection and immunity. 2006; 74(6); 3498-3506. [PubMed: 16714581].