Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

ruvB

Victor ID 4932
Gene Name ruvB
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID 1253415
NCBI Protein GI 16765236
Locus Tag STM1894
Genbank Accession AE006468
Protein Accession NP_460851
Taxonomy ID 700720
Gene Starting Position 1989053
Gene Ending Position 1990063
Gene Strand (Orientation) -
Protein Name Holliday junction DNA helicase RuvB
Protein pI 5.03
Protein Weight 34934.59
Protein Length 336
Protein Note promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
DNA Sequence 
>gi|16763390:1989053-1990063 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome
GCTAAGGCATCTCTGGCGGCGTGATCCCGAAATGGTTCCAGGCGCGCACCGTTGCCATACGCCCACGCGG
CGTACGCTGCAAAAAGCCTTGCTGAATCAGATACGGCTCCAGCACATCCTCAATGGTTTCACGCTCTTCG
CCAATCGCCGCCGCCAGGTTATCCAGTCCCACCGGACCACCGAAGAATTTATCAATAACCGCCAGCAGCA
GCTTGCGATCCATATAGTCAAACCCTTCCGCATCGACGTTCAGCATATCCAGCGCCTGCGCGGCAATTTC
CGCTGAAATAGCCCCGTCATGCTTCACCTCAGCAAAATCACGCACACGTCTGAGCAGACGGTTGGCTATA
CGCGGCGTACCGCGCGCCCGACGCGCCACTTCCAGCGCGCCGTCATCGCTCATCTCAAGCCCCATGTGCC
TTGCGCTGCGCCCAACGATGTGCTGCAGATCGGGCACCTGGTAGAACTCCAGGCGCTGCACAATACCAAA
ACGGTCACGTAGCGGGGACGTTAACGACCCGGCGCGCGTCGTCGCGCCAATGAGCGTAAACGGCGGCAGA
TCGATCTTAATTGAACGTGCGGCAGGCCCTTCGCCAATCATAATATCCAACTGGTAATCTTCCATCGCCG
GATAGAGTACCTCTTCCACCACCGGTGAAAGCCGGTGAATCTCATCAATAAACAGCACATCATGCGGTTC
AAGATTGGTGAGCATAGCCGCCAGATCGCCTGCTTTTTCCAGCACCGGGCCGGACGTGGTTCGGAGATTG
ACGCCCATTTCATTGGCAACGATATTCGCCAGAGTCGTTTTACCTAACCCTGGCGGGCCGAAAATCAGCA
AGTGATCTAGTGCGTCGCCACGCCGTTTTGCCGCCTGAATAAAGATCTCCATCTGGGAGCGCACCTGCGG
TTGGCCGACATATTCCGCCAATAACTTCGGGCGAATGGCGCGATCGGCGACGTCTTCTGCGATCGTGGCG
CCTGCTGAAATCAGGCGATCTGCTTCTATCA
Protein Sequence 
>gi|16765236|ref|NP_460851.1| Holliday junction DNA helicase RuvB [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
MIEADRLISAGATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKRRGDALDHLLIFGPPGLGKTT
LANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIG
EGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQHIVGRSARHMGLEMSDDGAL
EVARRARGTPRIANRLLRRVRDFAEVKHDGAISAEIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGP
VGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A ruvB mutant is attenuated in mice (Choi et al., 2010).
COG COG2255L, under L: Replication, recombination and repair
References
Choi et al., 2010: Choi J, Shin D, Ryu S. Salmonella enterica serovar Typhimurium ruvB mutant can confer protection against salmonellosis in mice. Vaccine. 2010; 28(39); 6436-6444. [PubMed: 20670908].