Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

guaB

Victor ID 4922
Gene Name guaB
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Enteritidis str. P125109
NCBI Gene ID 6949287
NCBI Protein GI 207857921
Locus Tag SEN2491
Genbank Accession AM933172
Protein Accession YP_002244572
Taxonomy ID 550537
Gene Starting Position 2625484
Gene Ending Position 2626950
Gene Strand (Orientation) -
Protein Name inosine 5'-monophosphate dehydrogenase
Protein pI 6.59
Protein Weight 47186.87
Protein Length 488
Protein Note catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
DNA Sequence 
>gi|207855516:2625484-2626950 Salmonella enterica subsp. enterica serovar Enteritidis str. P125109 chromosome, complete genome
ATCAGGAGCCCAGACGGTAGTTCGGGGACTCTTTGGTGATGGTCACGTCGTGAACGTGGCTTTCCTGGAT
ACCCGCACCGCTGATACGCACAAACTCCGCTTTAGTACGCAGTTCGTCGATGGTAGCACAACCGGTCAGC
CCCATACAGGAGCGCAGGCCGCCCATCTGCTGGTGAATGATCTCTTTCAGGCGACCTTTATAGGCTACGC
GGCCTTCGATACCTTCCGGCACCAGTTTGTCGGCGGCGTTGTCGCTCTGGAAGTAACGGTCGGAGGAACC
TTTGGACATCGCGCCCAGAGAACCCATACCGCGATAAGATTTGTAAGAACGGCCCTGGTAGAGTTCGATT
TCGCCCGGGGATTCTTCGGTACCGGCCAGCATAGAACCCACCATTACCGCGCTCGCGCCTGCGGCGATGG
CTTTGGCGATGTCGCCGGAGAAACGGATACCGCCGTCAGCGATAACCGGAATCCCGGTGCCTTCCAGCGC
TTCCACCGCGTCAGAAACAGCGGTGATCTGCGGAACGCCCACACCAGTCACGATACGAGTCGTACAGATG
GAACCCGGGCCGATACCCACTTTCACCGCGCTGCAACCGGCTTCCGCCAGTGCGCGAGCGCCTGCGCCCG
TCGCAACGTTGCCGCCGATGATTTGCAGGTCAGGATATTTAGCACGCGTCTCACGGATACGTTGCAACAC
GCCTTCAGAGTGACCGTGAGAGGAGTCGATCAGCAGTACGTCAACGCCTGCCGCCACCAGCGCGTCAACG
CGCTCTTCGTTGCCCGCGCCTGCGCCGACCGCCGCGCCGACACGTAAACGGCCCTGCTCATCTTTACAGG
AGTTTGGTTTACGTTCCGCTTTCTGGAAATCTTTTACGGTAATCATGCCAAGCAGATGGAAGTTATCATC
AACGACCAGCGCTTTTTCTACGCGTTTTTCGTGCATTTTTGCCAGCACGACTTCACGGGCTTCGCCTTCA
CGAACGGTCACCAGACGCTCTTTCGGTGTCATGTAGACACTCACCGGCTGGTTCAGGTCAGTCACAAAAC
GCACGTCACGACCGGTGATGATACCCACCAGCTCGTTATCTTCAGTCACCACCGGATAGCCCGCAAAACC
GTTACGCTCGGTCAGGGCTTTCACTTCATGCAACGTGGTGGTTGGCAGGACGGTCTGCGGGTCGGTCACT
ACGCCGGACTCGTGTTTCTTCACGCGGCGAACTTCTTCCGCCTGGCGCTCAATAGACATGTTTTTGTGGA
TAAAACCAATGCCGCCTTCCTGGGCCAGGGCAATTGCCAGGCGCGCTTCCGTCACGGTGTCCATCGCCGC
AGAAAGCATAGGAATATTCAGACGAATAGTTTTCGTCAACTGCGTGCTGAGATCGGCAGTATTCGGCAAA
ACGGTGGAGTGAGCGGGAACAAGGAGGACGTCGTCAAACGTCAGAGCTTCTTTAGCGATACGTAGCA
Protein Sequence 
>gi|207857921|ref|YP_002244572.1| inosine 5'-monophosphate dehydrogenase [Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]
MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARLAIALAQEGGIGFI
HKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLHEVKALTERNGFAGYPVVTEDNELVGIITGRDVR
FVTDLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRVEKALVVDDNFHLLGMITVKDFQKAERKPNS
CKDEQGRLRVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVAT
GAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVSDAVEALEGTGIPVIADGGIRFSGDIAKA
IAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGR
VAYKGRLKEIIHQQMGGLRSCMGLTGCATIDELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: guaB mutant is attenuated in BALB/c mice (Adriaensen et al., 2007).
COG COG0516F, under F: Nucleotide transport and metabolism
References
Adriaensen et al., 2007: Adriaensen C, De Greve H, Tian JQ, De Craeye S, Gubbels E, Eeckhaut V, Van Immerseel F, Ducatelle R, Kumar M, Hernalsteens JP. A live Salmonella enterica serovar Enteritidis vaccine allows serological differentiation between vaccinated and infected animals. Infection and immunity. 2007; 75(5); 2461-2468. [PubMed: 17261603 ].