Victors

cbiA
Victor ID	4920
Gene Name	cbiA
Sequence Strain (Species/Organism)	Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91
NCBI Gene ID	6923268
NCBI Protein GI	205353181
Locus Tag	SG2061
Genbank Accession	AM933173
Protein Accession	YP_002226982
Taxonomy ID	550538
Gene Starting Position	2106950
Gene Ending Position	2108329
Gene Strand (Orientation)	-
Protein Name	cobyrinic acid a,c-diamide synthase
Protein pI	6.59
Protein Weight	47041.13
Protein Length	459
Protein Note	responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid
DNA Sequence	>gi\|205351346:2106950-2108329 Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91 chromosome, complete genome GTCATAATACGCGCCTCGCCGCCGCCAGCCAGTGCTGCAACATTTCCGGACGCTGGGCGAAATGGACGTG CAGATAGCTGGCAAACGTGTTGCCTGTCTGCCAGCCGCCAGTCCATTCCTGTAACACGCGGCCATCGCGA ACCTTACGACAGGCCATAACGGCGGGTGTTTCGGGGATAAAATCTGAGTAGTGAAATTCATGGCCGCGCA CTATCTCGCCAAGCGCCGCCAATAGCGTTGGCTGCATAGCCTGCGCCTCACAGTAGCCAAAGCGGGTAAG TCGCTTACCCATTTTGCTGTGACCGGGGATAATATTCGCCATCTGATGAATTTCCCCACCGCTATCCTCC AGAGTGCTCCCCAGATACATCAGACCGCCACACTCCGCGTAAATCGCCACGCCGCGCTGATGCGCCGCCC GCAAATGTTTTAACATCGCCGTATTTGCCGCCAGATCCGCGGCGTATAATTCAGGATATCCACCGCCCAG CCAGATCATCTGACAATCAGGCAATGCGCGGTCATGCAGTGGGCTAAAACGCACAATGTTAACGCCGGCA CGCTCCAGAAAATCGATGTTATCGGGATAATAAAAGTTAAAGGCCTCATCATCCGCCAGAGCAAGCGTCA GCCCTGCCCCCGCTGTGTTATCGGGGCGCTCAGGCCACATTCCCGTCGGAAGCGCTGATAACACGCTCAG CGAGAGTAGCGCATCCACATCCACTGTTTGTTCCAGCGAGGCGGCAAAATCATGCCATGATTGCTGATTG ACGAGGGATTCTCTGGCGGTAATCAACCCCAGGTGGCGTTCAGGTAATGCGACGCCGTCGCAAGGAGGAA CATACCCCAGTACCGGCCGTGAGCAATAATGTTCAATGGCATTTTTGAGGAGCTGATAGTGGGCGTCGCT AGTGACGCGATTCACAATCACGCCCGCGAGGTTGAGGGTCGGGTCGAAGTGCTGAAATCCCATAACGGTA GCCGCAAGCGACGTTGAAACAGCCTTGCCGTCCACCAGTAGGATGACCGGGCAACCAAGCTGTTTGGCCA TCGCGGCTGTGCTGCAGTAATTGGGGTCGACGCCATAGCCGTCATACAGCCCCATGACGCCTTCAATGAC AGCGATATCCGCCTGCCGCATTTGTTCGCAAAATAAGGCGTTGAGAACAGGAGGAGGAAGCATGAAACTG TCAAGATTACGGGACGCCACGCCACAGATAGCGGTATGCCAGCCGGTATCAAGGTAATCTGGCCCAACTT TAAACGGCTGTACGCGCAGCGCGCGTTTTTGCAGCAGCCTCAACAAACCAAGCGTCACCGTGGTTTTGCC GCAACCGCTTCCTGTGCCTGCAAGAATAAATGCGTGATGCCTTGCCGCCA
Protein Sequence	>gi\|205353181\|ref\|YP_002226982.1\| cobyrinic acid a,c-diamide synthase [Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91] MAARHHAFILAGTGSGCGKTTVTLGLLRLLQKRALRVQPFKVGPDYLDTGWHTAICGVASRNLDSFMLPP PVLNALFCEQMRQADIAVIEGVMGLYDGYGVDPNYCSTAAMAKQLGCPVILLVDGKAVSTSLAATVMGFQ HFDPTLNLAGVIVNRVTSDAHYQLLKNAIEHYCSRPVLGYVPPCDGVALPERHLGLITARESLVNQQSWH DFAASLEQTVDVDALLSLSVLSALPTGMWPERPDNTAGAGLTLALADDEAFNFYYPDNIDFLERAGVNIV RFSPLHDRALPDCQMIWLGGGYPELYAADLAANTAMLKHLRAAHQRGVAIYAECGGLMYLGSTLEDSGGE IHQMANIIPGHSKMGKRLTRFGYCEAQAMQPTLLAALGEIVRGHEFHYSDFIPETPAVMACRKVRDGRVL QEWTGGWQTGNTFASYLHVHFAQRPEMLQHWLAAARRVL
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: A cbiA mutant, in combination with a cobS mutation, is attenuated in chickens (Penha et al., 2010).
COG	COG1797H, under H: Coenzyme transport and metabolism
References	*Penha et al., 2010:* Penha Filho RA, de Paiva JB, da Silva MD, de Almeida AM, Berchieri A Jr. Control of Salmonella Enteritidis and Salmonella Gallinarum in birds by using live vaccine candidate containing attenuated Salmonella Gallinarum mutant strain. Vaccine. 2010; 28(16); 2853-2859. [PubMed: 20153354].


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cbiA