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wbtI

Victor ID 4913
Gene Name wbtI
Sequence Strain (Species/Organism) Francisella tularensis subsp. holarctica FTNF002-00
NCBI Gene ID 5522688
NCBI Protein GI 156502002
Locus Tag FTA_0635
Genbank Accession CP000803
Protein Accession YP_001428067
Taxonomy ID 458234
Gene Starting Position 590832
Gene Ending Position 591914
Gene Strand (Orientation) +
Protein Name DegT/DnrJ/EryC1/StrS family sugar aminotransferase
Protein pI 6.8
Protein Weight 37905.36
Protein Length 360
Protein Note component of putative O antigen gene complex
DNA Sequence 
>gi|156501369:590832-591914 Francisella tularensis subsp. holarctica FTNF002-00 chromosome, complete genome
AATGAGTAAAGTAAATGTAACAAAACCATATTTACCAGATATAAATAAATATAAAAGCTATGTAAATAAA
ATATACAAAAATGGATGGCTTACTAATAATGGTCCGTTAGTGCAAGAGCTAGAAAAAAGACTTGCAAAGT
ATCTAGGTGTTAAAAATATAGTTTTAGTATCAAATGGTACAATTGCATTAGAAATCGCGTATAGAGCGTT
AGGAGTCAAAGGAAGTGCAATTACTACTCCATTTTCATTTGTCGCTACTACATCTTCATTGGTTTCTAAC
AATGTAAAACCAGTGTTTGTTGATATTGATGAGAATACTCTAAGTATAGACGTCTCTAAAATTAAGTATG
CTATTGAAGAGGATACTTCAGCTATTGTGCCAGTTCATGTGTTTGGAAATGGTTGTGAAGTTGAAAAAAT
AGACATGCTGGCTAAAAAACATAACTTAAAAGTTATTTATGATGCAGCACATGCTTTTGATGTTAAGTAT
AAGGGTGAGAGTATATTAAACTATGGTGATATTTCGACATTAAGTTTTCATGCAACAAAGATTTTTCATT
CTATTGAAGGAGGTGCGCTTATCATTAATGATGATAGTCTTGTTGAAAAAGTTCGTTATTTCATTAATTT
TGGTATAGAAAGCTCAGAATCAATACCTTACTTAGGTACTAATGCTAAAATGAATGAATTTGAGGCGGCT
ATGGGACTTTGTGTTCTAGATGATATTATAGAAATTAAGAGCAAAAGGAAAGTTATTACAGAGATATATG
AGGCTGGGTTAGATGGATTGGTAAAGTTTCAAGAACAGAATCAGCATTCTAGTAGGAATTATAGCTATTT
TCCAGTAATATTTAGGACTGAGGAGGAACTTCTCAGAGTACAGAAAGCACTAATACAAAATGATATAATA
TCGCGTAGATATTTTTATCCATCATTAGATAGTCTTAGTTATATAGAGCCAAAGCAGTATATGCCAATCT
CAAGAGATATATCTAAAAGAATATTATGTTTGCCAATTTATGCAGAGTTAGAAGACGATAAAATTAATAA
AATAATTAATAATATCAAAGAGGTTTCCTCATG
Protein Sequence 
>gi|156502002|ref|YP_001428067.1| DegT/DnrJ/EryC1/StrS family sugar aminotransferase [Francisella tularensis subsp. holarctica FTNF002-00]
MSKVNVTKPYLPDINKYKSYVNKIYKNGWLTNNGPLVQELEKRLAKYLGVKNIVLVSNGTIALEIAYRAL
GVKGSAITTPFSFVATTSSLVSNNVKPVFVDIDENTLSIDVSKIKYAIEEDTSAIVPVHVFGNGCEVEKI
DMLAKKHNLKVIYDAAHAFDVKYKGESILNYGDISTLSFHATKIFHSIEGGALIINDDSLVEKVRYFINF
GIESSESIPYLGTNAKMNEFEAAMGLCVLDDIIEIKSKRKVITEIYEAGLDGLVKFQEQNQHSSRNYSYF
PVIFRTEEELLRVQKALIQNDIISRRYFYPSLDSLSYIEPKQYMPISRDISKRILCLPIYAELEDDKINK
IINNIKEVSS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A wbtI mutant is attenuated in mice (Li et al., 2007).
COG COG0399M, under M: Cell wall/membrane/envelope biogenesis
References
Li et al., 2007: Li J, Ryder C, Mandal M, Ahmed F, Azadi P, Snyder DS, Pechous RD, Zahrt T, Inzana TJ. Attenuation and protective efficacy of an O-antigen-deficient mutant of Francisella tularensis LVS. Microbiology (Reading, England). 2007; 153(Pt 9); 3141-3153. [PubMed: 17768257].