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MIC2

Victor ID 4900
Gene Name MIC2
Sequence Strain (Species/Organism) Toxoplasma gondii
NCBI Protein GI 1923217
Other Database IDs CDD:29244
CDD:154951
Taxonomy ID 5811
Gene Strand (Orientation) ?
Protein Name micronemal protein MIC2
Protein Length 769
Protein Note Micronemal proteins: The Toxoplasma lytic cycle begins when the parasite actively invades a target cell. In association with invasion, T. gondii sequentially discharges three sets of secretory organelles beginning with the micronemes, which contain...; cd01471
Protein Sequence 
>gi|1923217|gb|AAB63303.1| micronemal protein MIC2 [Toxoplasma gondii]
MRLQREAVFGLMFACGMWMWPSEVAGGGWSIVDALRKRYDTSRGGDANGVDTSGVEDVIQSDSAIGAAEG
CTNQLDICFLIDSSGSIGIQNFRLVKQFLHTFLMVLPIGPEEVNNAVVTYSTDVHLQWDLQSPNAVDKQL
AAHAVLEMPYKKGSTNTSDGLKACKQILFTGSRPGREHVPKLVIGMTDGESDSDFRTVRAAKEIRELGGI
VTVLAVGHYVKHSECRSMCGCSGTSDDDSPCPLYLRADWGQLATAIKPMLKEVCKTLPQDAICSDWSAWS
PCSVSCGDGSQIRTRTEVSAPQPGTPTCPDCPAPMGRTCVEQGGLEEIRECSAGVCAVDAGCGVWGEWSA
WSASCGNATRKRERTRYNDPPPQGAGRRCENQDPPVLQEQTEEATLAPCITIPPTPPEWAAWSDCTVTCG
GGNRHRVRNALPPGLGSQNGESDESLVSKLWPGTDLRQEEACNTSPCPINATCGQFEEWSTCSVSCGGGL
KTRSRNPWNEDQQHGGLSCEQQHPGGRTETVTCNPQACPVDERPGEWAEWGECSVTCGDGVRERRRGKSL
VEAKFGGRTIDQQNEALPEDLKIKNVEYEPCSYPACGASCTYVWSDWNKCVCPMGYQARHAAVKFDYRNK
PCDLPTFETKACSCGETNPVPSEGTTPGAPGATGPEQPNQRPLPEGSDENETPTNEEGEQSKKESGSGIA
GAIAGGVIGGLILLGAAGGASYHYYLSSSVGSPSAEIEYEADDGATKVVMEEEKETLVPVDDDSDMWME
Molecule Role Virulence factor
Molecule Role Annotation MUTATION:A mic2 mutant is attenuated in mice (Huynh and Carruthers, 2006).
References
Huynh and Carruthers, 2006: Huynh MH, Carruthers VB. Toxoplasma MIC2 is a major determinant of invasion and virulence. PLoS pathogens. 2006; 2(8); e84. [PubMed: 16933991].