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FTL_0540

Victor ID 490
Gene Name FTL_0540
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3952679
NCBI Protein GI 89255947
Locus Tag FTL_0540
Protein Accession YP_513309.1
Taxonomy ID 119857
Gene Starting Position 523005
Gene Ending Position 524147
Gene Strand (Orientation) +
Protein Name Lipid-A-disaccharide synthase
DNA Sequence 
>gi|89255449:523005-524147 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
AATGAGAATAGGTATTGTAGCTGGAGAGCTTTCGGGCGATCAGTTAGGTGGCACACTAGTTGAGGCTTTA
AAGCAAAAATACCCTAATGCAATTATTGAAGGTATTGGTGGACCAAAAATGGCAGCCGCTGGTTTTAAAA
GCCTTTATCCGATGGATGCATTGTCGTTAATCGGCTTCTTAGAAATTATTTCAAAAGGTTTGCGCATATT
AAGTATCCGCCGTAAAATCATCAACTATTTTAAGCAAAATAAACCTGATATATTTATAGGCATAGATGCT
CCTGATTTTAATCTTACAGTTGAAAAAGAATTAAGATCTGCGGGTATCAAAACTATACATTATGTAAGTC
CTAAAATATGGGTTTGGCGTGAATACCGTATAAAAAAAATACGTAAAGCAACTGATAAAATATTAGCAAT
TTTACCTTTTGAAACTGAATACTATAAAAATAGACATAAATTTGAAGCTATATATGTTGGTCATCCATTA
GCGAAGAATATTCCAATACATATTGACCGAGCTAAATATAGAGATAAACTTGGATTAAAAGGTAGTTCTT
TACCAATATTATCAGTTTTACCAGGAAGTCGTACGACAGAAGTTTCAAGATTGTTGCCACTATTTTTGTT
AGCATTACAAAAATTGGTAGATGCTGGATATAAATTTAAAGCGATTATGCCCTTAGCTAAGCCATCATTA
AAACCATTATTTGCTAAATATAAAGAACAAATTGATAGTTTAGGTATCGAAGTTTTTGAAACGAATTCAC
ATGATGTTTTAAAAGCATCTGATTTAAGTTTATTGGCATCAGGAACAGCTACATTGGAGGCTATGTTATG
CAAATTACCTATGGTTGTAGGCTATAAACTATCATGGCTATCGGCTTTAATTGGTAGGATGCTTATTGGT
AATCATAGTTATTGGGCTTTCCCTAATATTTTGCATAAAAATGAAATTATCAAAGAATTAATACAAGAAG
ACTGTACAGTAGATAATTTATTTAGCGAGTTAAAAAGGTTGTTTGATGATAAGCGGCGTAATGATTATAT
AGTAGAAGAATTTGAAAAAATTCACAAAGAAATGGTTATTGATACTGAGAGTAAGATCATTCAAGTATTA
GATACTATGATAGAAAAATCTTA
Protein Sequence 
>gi|89255947|ref|YP_513309.1| lipid-A-disaccharide synthase [Francisella tularensis subsp. holarctica LVS] MRIGIVAGELSGDQLGGTLVEALKQKYPNAIIEGIGGPKMAAAGFKSLYPMDALSLIGFLEIISKGLRILSIRRKIINYFKQNKPDIFIGIDAPDFNLTVEKELRSAGIKTIHYVSPKIWVWREYRIKKIRKATDKILAILPFETEYYKNRHKFEAIYVGHPLAKNIPIHIDRAKYRDKLGLKGSSLPILSVLPGSRTTEVSRLLPLFLLALQKLVDAGYKFKAIMPLAKPSLKPLFAKYKEQIDSLGIEVFETNSHDVLKASDLSLLASGTATLEAMLCKLPMVVGYKLSWLSALIGRMLIGNHSYWAFPNILHKNEIIKELIQEDCTVDNLFSELKRLFDDKRRNDYIVEEFEKIHKEMVIDTESKIIQVLDTMIEKS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_0540 mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0763M, under M: Cell wall/membrane/envelope biogenesis
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].