Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

icsB from Shigella flexneri 5a

Victor ID 49
Gene Name icsB from Shigella flexneri 5a
Sequence Strain (Species/Organism) Shigella flexneri 5a
NCBI Gene ID 876528
NCBI Protein GI 13449078
Locus Tag pWR501_p139
Protein Accession NP_085294.1
Other Database IDs UniProtKB-ID: ICSB_SHIFL
UniRef100: UniRef100_P33546
UniRef90: UniRef90_P33546
UniRef50: UniRef50_P33546
UniParc: UPI000012D189
EMBL: M86530
EMBL: AL391753
EMBL: AF348706
EMBL: AY206439
EMBL: AF386526
EMBL-CDS: AAD15221.1
EMBL-CDS: CAC05807.1
EMBL-CDS: AAK18450.1
EMBL-CDS: AAP78995.1
EMBL-CDS: AAL72354.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093099
EnsemblGenome_TRS: EBESCT00000094055
EnsemblGenome_PRO: EBESCP00000090262
GenomeReviews: AF386526_GR
KEGG: sfl:CP01
Taxonomy ID 623
Plasmid No pWR501
Gene Starting Position 107588
Gene Ending Position 109072
Gene Strand (Orientation) -
Protein Name invasion protein
DNA Sequence 
>gi|13448939:107588-109072 Shigella flexneri 5a virulence plasmid pWR501, complete sequence
TCTATATATTAGAATGAGAGTTATTCAATAAAAGCTTATTGATCTGTAATAAGTCGTGAATGTAAAGTTT
GGTTCCAAGATCTGGCGATTTAAGAGAATTGTAATAATCAATAATTTTTATTGATTTTTCGATGATTTCT
TCTTTTTTATCTGTTGCTTCGGTTTTTAATTCGTTTAATACACGAGTCATATTGCTGGGTGCTGATTTTA
CTAAGTATGAGTGGCAAGCGTTGATGACCGCATCAAAGTCTTCTGAAGATACATTTTCAGTAGGATGTTT
GTAAAGTGAAATTGATAAAGGCTTGAATGTTTTTGGTGTGTGGATAAGGTTAATTTTATTGAAACTTTTA
AGATAGCTGCGTCGTAATTGAGTCAATCTGGAAAGATCAAAATCAGATTCAATATACTTCATTATTTCGT
TATAAGACTGATTGAGACTTTCAATGCGTTGCCTAACTTTATTTGCATACGCGTATACATCGTTAGGTGT
AGCAACCAATTTAACGTCAGGGAGTGGAAAGTATATTTCAGAATTTCCTGCTTTAAGAACATTAAGTGCC
ATACCAGCACAGTTTTCAGATTTACTGATTAATTTATAATTTGCCAATTGTCTGAAAGCATCTGCTTTCT
TTTTGCATATAAATTTTGACATGTTTGTTTCATCAAGGCCAAAAAGGTTATGGCTGATTTTACCATCCTT
TGTTTTATTATCACCTGATAATGGAATGTATACTTTATCAGCACTGACCCCCCAATAACCATAGGGGTCT
TTTTTTTGATTAGCTCTGGGAAAAAATATTTTTTTGTTGTTATTTTGATCTTGTTTTGAATTTAATAAGT
TTCTAACCTCTTGGCCTGCATCAAGTCTTTCGGCTGTTTGCTCTGAAATCATATTTAGTTTGTCTTGCTT
ATAGGTATCGACACTGTAACCTGAGCGTTTTTCAAAAAGGTAGTTTATTTCTGTATCTTTTGTAACATTC
CCGCCGGGATACCAGCTGAGATAGGTATGAGTTGGTTCCTGTAGTAAATTGTTTTTTATACTGATACTAG
TATGCCCTAAATGGGTTATGCCTCTATTTCCCCAGCAACGAAAAACTAAATGTCTTTCAAGATTTTTGGC
TGTACCGATGCCATGAAAACGCTCTGCGGTATTCAACATTAATTTGATGTCTCTACCTGTGAAAGAGTGT
TGAATTGAGTTTTTAGCTGCTTCATAGGCGGCAAACGCACTTTCTGCAGATTTTTCGCTAGCTAATGTAT
TGAGGAAAAGCAATAAGGATTTTTGATTCTCTAGTCGATAATTTTTTAGTTGTTCATTTAATATCTGTGA
ATTTATCTTTGCATTAATAGTGCTTAATGTTCTGAAAAAGAGATCCTTTAGGTTGAATTTCTGTGCTATC
AATATAGGTCCATGCTCTGTATCTTCAACGCGTATAGGCCCTTTTGTATTGCTTGCGTCAATGAAATTGC
TAATTTTGAGGCTCA
Protein Sequence 
>gi|13449078|ref|NP_085294.1| invasion protein [Shigella flexneri 5a str. M90T] MSLKISNFIDASNTKGPIRVEDTEHGPILIAQKFNLKDLFFRTLSTINAKINSQILNEQLKNYRLENQKSLLLFLNTLASEKSAESAFAAYEAAKNSIQHSFTGRDIKLMLNTAERFHGIGTAKNLERHLVFRCWGNRGITHLGHTSISIKNNLLQEPTHTYLSWYPGGNVTKDTEINYLFEKRSGYSVDTYKQDKLNMISEQTAERLDAGQEVRNLLNSKQDQNNNKKIFFPRANQKKDPYGYWGVSADKVYIPLSGDNKTKDGKISHNLFGLDETNMSKFICKKKADAFRQLANYKLISKSENCAGMALNVLKAGNSEIYFPLPDVKLVATPNDVYAYANKVRQRIESLNQSYNEIMKYIESDFDLSRLTQLRRSYLKSFNKINLIHTPKTFKPLSISLYKHPTENVSSEDFDAVINACHSYLVKSAPSNMTRVLNELKTEATDKKEEIIEKSIKIIDYYNSLKSPDLGTKLYIHDLLQINKLLLNNSHSNI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: icsB mutants are attenuated in guinea pig eyes (Ogawa et al., 2003).
References
Ogawa et al., 2003: Ogawa M, Suzuki T, Tatsuno I, Abe H, Sasakawa C. IcsB, secreted via the type III secretion system, is chaperoned by IpgA and required at the post-invasion stage of Shigella pathogenicity. Molecular microbiology. 2003; 48(4); 913-931. [PubMed: 12753186].