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type b polysaccharide capsule

Victor ID 4887
Gene Name type b polysaccharide capsule
Sequence Strain (Species/Organism) Haemophilus influenzae
Gene Strand (Orientation) ?
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutations in the genes hcsA and/or hcsB resulted in diminished polysaccharide b capsule, and were attenuated in neonatal mice (Sukupolvi-Petty et al., 2006).
References
Sukupolvi-Petty et al., 2006: Sukupolvi-Petty S, Grass S, St Geme JW 3rd. The Haemophilus influenzae Type b hcsA and hcsB gene products facilitate transport of capsular polysaccharide across the outer membrane and are essential for virulence. Journal of bacteriology. 2006; 188(11); 3870-3877. [PubMed: 16707679].