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hyaluronic acid capsule

Victor ID 4882
Gene Name hyaluronic acid capsule
Sequence Strain (Species/Organism) Streptococcus pyogenes
Gene Strand (Orientation) ?
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A mutant acapsular strain TX72 (with a mutation in hasA) was avirulent in mice and sensitive to phagocytic killing in vitro (Wessels et al., 1994).
References
Wessels et al., 1994: Wessels MR, Goldberg JB, Moses AE, DiCesare TJ. Effects on virulence of mutations in a locus essential for hyaluronic acid capsule expression in group A streptococci. Infection and immunity. 1994; 62(2); 433-441. [PubMed: 8300204].