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kpsE

Victor ID 4875
Gene Name kpsE
Sequence Strain (Species/Organism) Campylobacter jejuni subsp. jejuni 81116
NCBI Gene ID 5617759
NCBI Protein GI 157415671
Locus Tag C8J_1352
Genbank Accession CP000814
Protein Accession YP_001482927
Taxonomy ID 407148
Gene Starting Position 1370752
Gene Ending Position 1371870
Gene Strand (Orientation) -
Protein Name capsular polysaccharide ABC transporter
Protein pI 7.1
Protein Weight 40829.39
Protein Length 372
DNA Sequence 
>gi|157414322:1370752-1371870 Campylobacter jejuni subsp. jejuni 81116, complete genome
TTTAATACTTATGCTCCTCTATTATCATTTTAATAAATTTAACAATCCCAAAAATCAAAGATAATACAAT
AAATGCTGTTAAAATATCATAAATTCTTTCAGGATATTTTGCGCTTTCTGGAATATCTGGACTTTGGATG
ATGACAAGTTGTTTTATTTTTCTTAATGCTTCTATTCTAGCACTTTCATAAGCTTTTAAAGCTGCTTCAT
AAGCTTTTTGCGCAAAAGTAGCTTCTATAGTTAAATCCTGAAATTTAGCAGCCAAATCGTTAAGCTTTTG
AGAAGAATTGTTAGCTGAAATTTTAGATTTTTCCCTTAAAAGCTGTTTTTTAATCGCTTCAATTTCTGCT
TTAAGTGCTACTACTTCAGGTGCTGCATCATTCATATAGCTTTGTAAAGTTAAAAGTTTAGCTTCTTTTT
GAGCTAAATTAGCCTCAATTTGCGCAACTAAACTTGCTTTAGTTTCAGCTTGTTTTAAAGGATCAAAAAC
TCCATATTTATTTTGAAAAGCAATCAAATCATTTTGTGCTTTTTGATAACGTTCTTTGTATTTTTGCACT
TCATTTTCAGCAAAAGCCATTTGCTCTCTAGCTGCTTTATGAGAGATTTCGTTGATAAATTTTTCGCTTT
CTTGCATAATAGCTTGAGCAATCAAATGAGCTGATTTAGGTGTAAAACCCTCTACTTCAACTTTTAAAAG
TTTAGTGGTTTCATCCGTATGAACCTTAACTCTTGCTTGGTAGTATTTAAGATAAGATTCTATCGAGCTT
GAATCCCAAATTTTAAAAGGTAAATCTATATGTTGCTCTTGATAAAGATTTTTAAGTTTGATTTTTTCAT
CCAAAATCTTTAACATATCACTTGATTCTATATAACCTTTTAGATAATTTAAATCTTCGCTTGCTGTAGA
AGTACTACTAAGCAAAGACAAGATTCCACTTGTTTGAGCACTTTCTCCACTTGTTGATCTAACATCTAAA
ATCATCGTGCTTACATATCTTGGTGCTGCAATCAATGTATAATAAATCACAACAAAAATCATTATAAACC
AAACAATTTTAAAAGAATCAAATATACTTAAATCTTTGATTTTTTCTAATAAAGTTTTATTTTCTTCCA
Protein Sequence 
>gi|157415671|ref|YP_001482927.1| capsular polysaccharide ABC transporter [Campylobacter jejuni subsp. jejuni 81116]
MEENKTLLEKIKDLSIFDSFKIVWFIMIFVVIYYTLIAAPRYVSTMILDVRSTSGESAQTSGILSLLSST
STASEDLNYLKGYIESSDMLKILDEKIKLKNLYQEQHIDLPFKIWDSSSIESYLKYYQARVKVHTDETTK
LLKVEVEGFTPKSAHLIAQAIMQESEKFINEISHKAAREQMAFAENEVQKYKERYQKAQNDLIAFQNKYG
VFDPLKQAETKASLVAQIEANLAQKEAKLLTLQSYMNDAAPEVVALKAEIEAIKKQLLREKSKISANNSS
QKLNDLAAKFQDLTIEATFAQKAYEAALKAYESARIEALRKIKQLVIIQSPDIPESAKYPERIYDILTAF
IVLSLIFGIVKFIKMIIEEHKY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: the capacity of a kpsE mutant to adhere to the INT-407 cells was reduced 20-fold, and the invasion capability of the kpsE mutant was two-fold lower than that of the wild type (Bachtiar et al., 2007).
COG COG3524M, under M: Cell wall/membrane/envelope biogenesis
References
Bachtiar et al., 2007: Bachtiar BM, Coloe PJ, Fry BN. Knockout mutagenesis of the kpsE gene of Campylobacter jejuni 81116 and its involvement in bacterium-host interactions. FEMS immunology and medical microbiology. 2007; 49(1); 149-154. [PubMed: 17266722].