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LPS

Victor ID 4868
Gene Name LPS
Sequence Strain (Species/Organism) Shigella
Gene Strand (Orientation) ?
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: galU mutant (which has LPS lacking O-antigen) is attenuated in intracellular spread in HeLa cells (Sandlin et al., 1995).
References
Sandlin et al., 1995: Sandlin RC, Lampel KA, Keasler SP, Goldberg MB, Stolzer AL, Maurelli AT. Avirulence of rough mutants of Shigella flexneri: requirement of O antigen for correct unipolar localization of IcsA in the bacterial outer membrane. Infection and immunity. 1995; 63(1); 229-237. [PubMed: 7528731].