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|
LPS |
| Victor ID |
4863 |
|
Gene Name |
LPS |
|
Sequence Strain (Species/Organism) |
Haemophilus influenzae |
|
Gene Strand (Orientation) |
? |
|
Molecule Role |
Virulence factor |
|
Molecule Role Annotation |
MUTATION: isogenic sialic acid-deficient LPS mutants (disrupted sialyltransferase or CMP-acetylneuraminic acid synthetase genes) were profoundly attenuated in chinchillas (Bouchet et al., 2003). |
| References |
Bouchet et al., 2003: Bouchet V, Hood DW, Li J, Brisson JR, Randle GA, Martin A, Li Z, Goldstein R, Schweda EK, Pelton SI, Richards JC, Moxon ER. Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(15); 8898-8903. [PubMed: 12855765].
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