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LPS

Victor ID 4862
Gene Name LPS
Sequence Strain (Species/Organism) Brucella
Gene Strand (Orientation) ?
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a wboA mutant led to the abolition of the O-side-chain synthesis resulting in rough LPS phenotype which was attenuated in mice. Restoration of wboA gene restored O-side-chain synthesis (McQuiston et al., 1999).
References
McQuiston et al., 1999: McQuiston JR, Vemulapalli R, Inzana TJ, Schurig GG, Sriranganathan N, Fritzinger D, Hadfield TL, Warren RA, Lindler LE, Snellings N, Hoover D, Halling SM, Boyle SM. Genetic characterization of a Tn5-disrupted glycosyltransferase gene homolog in Brucella abortus and its effect on lipopolysaccharide composition and virulence. Infection and immunity. 1999; 67(8); 3830-3835. [PubMed: 10417145 ].