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LPS |
| Victor ID |
4862 |
|
Gene Name |
LPS |
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Sequence Strain (Species/Organism) |
Brucella |
|
Gene Strand (Orientation) |
? |
|
Molecule Role |
Virulence factor |
|
Molecule Role Annotation |
MUTATION: a wboA mutant led to the abolition of the O-side-chain synthesis resulting in rough LPS phenotype which was attenuated in mice. Restoration of wboA gene restored O-side-chain synthesis (McQuiston et al., 1999). |
| References |
McQuiston et al., 1999: McQuiston JR, Vemulapalli R, Inzana TJ, Schurig GG, Sriranganathan N, Fritzinger D, Hadfield TL, Warren RA, Lindler LE, Snellings N, Hoover D, Halling SM, Boyle SM. Genetic characterization of a Tn5-disrupted glycosyltransferase gene homolog in Brucella abortus and its effect on lipopolysaccharide composition and virulence. Infection and immunity. 1999; 67(8); 3830-3835. [PubMed: 10417145 ].
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