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LOS

Victor ID 4860
Gene Name LOS
Sequence Strain (Species/Organism) Neisseria meningitidis
Gene Strand (Orientation) ?
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Isolates with an immunotype other than L3,7,9 were less virulent in infant mouse model than N. menigitidis strains with the L2,7,9 LOS immunotype (Mackinnon et al., 1993).
References
Mackinnon et al., 1993: Mackinnon FG, Borrow R, Gorringe AR, Fox AJ, Jones DM, Robinson A. Demonstration of lipooligosaccharide immunotype and capsule as virulence factors for Neisseria meningitidis using an infant mouse intranasal infection model. Microbial pathogenesis. 1993; 15(5); 359-366. [PubMed: 7912406].