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FTL_0387

Victor ID 485
Gene Name FTL_0387
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3952567
NCBI Protein GI 89255798
Locus Tag FTL_0387
Protein Accession YP_513160.1
Taxonomy ID 119857
Gene Starting Position 355653
Gene Ending Position 356843
Gene Strand (Orientation) -
Protein Name aspartate aminotransferase
DNA Sequence 
>gi|89255449:355653-356843 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
CTTATTTACTGTTATAAGCTTTGATAGCTTTATCTAAGAGCTCTAGAGCTCTTCTTAGTGATTTCTCTTC
TAAGATATATGCGATTCTTATTTCATCTTTACCTAGACCTTTGGTTGCATAGAAGTCACCAGCAGGAGAG
ATCATCACAGTTTCGCGATTATCTTCAAAGTCTGTTAGTAACCATAGTGCAAATTTCTCAGCATCATCGA
TAGGTAGTTTCGCGATTACATAGAAAGCACCAGTAGGCTTTTCACAAACTACATTATCCATTTTTGAAAG
AGCTTCGAAAGTGATATCTCTTCTTTTTTGGTATTCTGTATTTACTTCTTTTAGGTAATCTTCTGATACT
TCATAAAGAGCCGCAGCACCGATTTGCTCAAGAGTTGGCACACATAATCTAGCTTGGCATAGTTTAGTAG
CTTCCTTGATAAACTCTTTATTTTTTGAACAAAGAGAGCCAATTCTAGCACCACAAGCACTATAGCGCTT
AGATACCGAGTCAACGATAATCACACGATCTTCGACACCTTTGATATTGCCAAAAGATGTACATACAAGC
CCATCATAAGTAAACTCTCTATATACCTCATCACTGATAATAAATAGATCTTTTTCTTTAGCAACTTCTG
CTAAAGTTTCTAGCTCTTGTTTTGTATATACAACACCAGTAGGGTTACCAGGGTTAGAAATCATGATAGC
ACGAGTTTTATCAGTTACACATGCTAGGATCTCTTCTTTTGAAGGTAAATGGAAACCTTCTTCAGCTTTT
GTTGTGATTGGTCTTATAGACACATCAACAGCAGTTGTGAAGCCATTATAGTTTGTATAGAAAGGTTCTG
GTACAAGTATCTCATCACCAGCATTACAAGTAGCAATCGCAGCAAATATTAGCGCTTCAGAACCACCGTT
AGTGATTAAGATTTCATCCTCAGCAAAGTCCATATCAAATCTTTTGTAGTATTTTGATATAGCCTTGATT
AAGCTTGGCTCACCACTTGCTATAGAGTAGGCGATAGTCTCTTTGTCATAAGCTCTGATAGCATCCATAA
ACTCATTAGGAGTTTTGATATCAGGCTGACCAATATTAAGGTAGTATACCTTTTTACCTTGTTTTTCTGC
TTGAATAGAATACGGCACTAACTTACGTACTGGAGAGGCTTGCATTGCCTTTACTCTTCTTGATAATTGC
A
Protein Sequence 
>gi|89255798|ref|YP_513160.1| aspartate aminotransferase [Francisella tularensis subsp. holarctica LVS] MQLSRRVKAMQASPVRKLVPYSIQAEKQGKKVYYLNIGQPDIKTPNEFMDAIRAYDKETIAYSIASGEPSLIKAISKYYKRFDMDFAEDEILITNGGSEALIFAAIATCNAGDEILVPEPFYTNYNGFTTAVDVSIRPITTKAEEGFHLPSKEEILACVTDKTRAIMISNPGNPTGVVYTKQELETLAEVAKEKDLFIISDEVYREFTYDGLVCTSFGNIKGVEDRVIIVDSVSKRYSACGARIGSLCSKNKEFIKEATKLCQARLCVPTLEQIGAAALYEVSEDYLKEVNTEYQKRRDITFEALSKMDNVVCEKPTGAFYVIAKLPIDDAEKFALWLLTDFEDNRETVMISPAGDFYATKGLGKDEIRIAYILEEKSLRRALELLDKAIKAYNSK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_0387 mutant was attenuated for infection in a mouse lung (Su et al., 2007)
COG COG0436E, under E: Amino acid transport and metabolism
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].