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irpA

Victor ID 4842
Gene Name irpA
Sequence Strain (Species/Organism) Listeria monocytogenes EGD
NCBI Protein GI 1403357
Other Database IDs CDD:152789
CDD:176844
CDD:29015
CDD:116777
HSSP: Q8Y6A8
InterPro: IPR001611
InterPro: IPR012569
UniProtKB/TrEMBL: Q799Z7
Taxonomy ID 1639
Gene Strand (Orientation) ?
Protein Name internalin-related protein A precursor
Protein Length 297
Protein Note Bacterial adhesion/invasion protein N terminal; pfam12354
Protein Sequence 
>gi|1403357|emb|CAA67098.1| internalin-related protein A precursor [Listeria monocytogenes]
MLKKNNWLQNAVIAMLVLIVGLCINMGSGTKVQAESIQRPTPINQVFPDPGLANAAKQNLGKQSVTDLVS
QKELSGVQNFNGDNSNIQSLAGMQFFTNLKELHLSHNQISDLSPLKDLTKLEELSVNRNRLKNLNGIPSA
CLSRLFLDNNELRDTDSLIHLKNLEILSIRNNKLKSIVMLGFLSKLEVLDLHGNEITNTGGLTRLKKVNW
IDLTGQKCVNEPVKYQPELYIANAVKDPDGRWISPYYISNGGSYVDGCVLWELPVYTDEVSYKFSEYINV
GETEAIFDGTVTQPIKN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: irpA mutant is attenuated in mice (Domann et al., 1997).
References
Domann et al., 1997: Domann E, Zechel S, Lingnau A, Hain T, Darji A, Nichterlein T, Wehland J, Chakraborty T. Identification and characterization of a novel PrfA-regulated gene in Listeria monocytogenes whose product, IrpA, is highly homologous to internalin proteins, which contain leucine-rich repeats. Infection and immunity. 1997; 65(1); 101-109. [PubMed: 8975898].