Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

pmm

Victor ID 4830
Gene Name pmm
Sequence Strain (Species/Organism) Leishmania mexicana M379
NCBI Protein GI 15387672
Other Database IDs CDD:162385
CDD:119389
CDD:187016
GOA:Q95ZD7
HSSP: O15305
InterPro: IPR005002
InterPro: IPR006379
UniProtKB/TrEMBL: Q95ZD7
Taxonomy ID 5665
Gene Strand (Orientation) ?
Protein Name phosphomannomutase
Protein Length 247
Protein Note HAD-superfamily hydrolase, subfamily IIB; TIGR01484
Protein Sequence 
>gi|15387672|emb|CAC59952.1| phosphomannomutase [Leishmania mexicana]
MGSKAILLFDVDGTLTPPRNPETHDMKEALLKARAAGFKLGVVGGSDFAKQKEQLGESILEDFDYVFSEN
GLLAYKDGKEFHRNSLLRALGNEKVVAFVKKCLHLIADLDIPVQRGTFVEFRNGMFNVSPIGRNCSQQER
DEFENLDKERHIREKLIRELKEAFPDYQLAYSVGGQISFDVFPKGWDKTYCLQFVENDFETIHFFGDKTS
EGGNDYEIFTDSRTIGHSVKTYKDTIAILEALLEDSR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: PMM mutant is attenuated in mice and murine macrophages (Garami et al., 2001).
References
Garami et al., 2001: Garami A, Mehlert A, Ilg T. Glycosylation defects and virulence phenotypes of Leishmania mexicana phosphomannomutase and dolicholphosphate-mannose synthase gene deletion mutants. Molecular and cellular biology. 2001; 21(23); 8168-8183. [PubMed: 11689705].