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hemO

Victor ID 4815
Gene Name hemO
Sequence Strain (Species/Organism) Leptospira interrogans serovar Lai str. 56601
NCBI Gene ID 1153745
NCBI Protein GI 24217247
Locus Tag LB_186
Genbank Accession AE010301
Protein Accession NP_714730
Taxonomy ID 189518
Chromosome No II
Gene Starting Position 181530
Gene Ending Position 182207
Gene Strand (Orientation) +
Protein Name heme oxygenase
Protein pI 5.41
Protein Weight 24692.24
Protein Length 225
Protein Note 1.14.99.3
DNA Sequence 
>gi|294653513:181530-182207 Leptospira interrogans serovar Lai str. 56601 chromosome chromosome II, complete sequence
AATGAGTTTAGCAACTATTTTACGAGAAGGGACATCTGAAGAGCACAAAGCCGCAGAAAGTTCTGCTTTC
ATTCGTTGTTTTATGAAAGGAATATTGGAAAAAGGGACTTATGCAAGACATCTAGAAGCGTTCTACTATG
TTTATGAGTCAATGGAAGAAGAGTTAGAACGTAATAAGAACAATCTGGTTTTAAAATCGATTTATTTTCC
GGAACTCTACCGTAAAAACGCACTTTTAGAAGATCTTCAGTTTTTTTACGGAACTTGGAAACCTAACGAT
CATCAACCAAGTGTGGCAACTCAAGACTATGTGCAAAGAATTCGTAAAATTTCAGAAACTCAACCGGAAC
TTTTGGCAGCTCATTCTTACGTTCGTTATTTGGGAGATCTTTCCGGTGGGCAAATTTTGAAAAAAGTAGC
GGCTAGAGCTTTAAATCTTCCAGAAGGAAAAGGAATTTCTTTTTACGAATTTCCTATGATTCAAGACATC
AATGGATTCAAACAAAATTATCGTACCGCGTTAGATTCCCTACCAGTCAACGATTCCGAAAAACAATCCA
TTCTTGCCGAATCAAAACAAGTTTTTCTTTTAAATCAGGGAATTTTTTCCGAACTGGAACAGGACTTAGT
TTCCGCAATCGGTAAGGAAACATATGATTCCGTTCTTGGAAAAGGTTA
Protein Sequence 
>gi|24217247|ref|NP_714730.1| heme oxygenase [Leptospira interrogans serovar Lai str. 56601]
MSLATILREGTSEEHKAAESSAFIRCFMKGILEKGTYARHLEAFYYVYESMEEELERNKNNLVLKSIYFP
ELYRKNALLEDLQFFYGTWKPNDHQPSVATQDYVQRIRKISETQPELLAAHSYVRYLGDLSGGQILKKVA
ARALNLPEGKGISFYEFPMIQDINGFKQNYRTALDSLPVNDSEKQSILAESKQVFLLNQGIFSELEQDLV
SAIGKETYDSVLGKG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hemO mutant is attenuated in hamsters (Murray et al., 2009).
References
Murray et al., 2009: Murray GL, Srikram A, Henry R, Puapairoj A, Sermswan RW, Adler B. Leptospira interrogans requires heme oxygenase for disease pathogenesis. Microbes and infection / Institut Pasteur. 2009; 11(2); 311-314. [PubMed: 19114124].